Ensure ® Plus Can Ensure Plus is a 1.5kcal/ml, high-protein, milkshake style oral nutritional supplement for people with, or at risk of developing, disease-related malnutrition. Ensure Plus is a rich, creamy drink that contains complete, balanced nutrition 1-2 when used in appropriate amounts, which provides calories, protein & carbohydrates to help you gain or maintain a healthy weight. 3-7