When does dlbcl relapse occur

The GC noted that most relapses of diffuse large B-cell lymphoma (DLBCL) will occur within the first 2-3 years following the end of first-line treatment and so recommended routine follow up during this time. The GC recognised that patients may experience symptoms suspicious of recurrence between routine appointments.

How often does DLBCL relapse?

Background: DLBCL has a 40% relapse rate in the rituximab era. Patients who relapse within a year do poorly even with salvage treatment.

How quickly can lymphoma relapse?

For classical HL, most relapses typically occur within the first three years following diagnosis, although some relapses occur much later. For patients who relapse or become refractory, secondary therapies are often successful in providing another remission and may even cure the disease.

What percent of DLBCL patients relapse?

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Approximately 30% to 40% of patients will develop relapsed/refractory (R/R) DLBCL, leading to significant morbidity and mortality.

How often does large B-cell lymphoma come back?

Despite a general favourable outcome in limited stage diffuse large B-cell lymphoma (DLBCL), relapses occur in about 10 to 20% of patients.