What is first line and second line medication?
Second-line treatment is treatment for a disease or condition after the initial treatment (first-line treatment) has failed, stopped working, or has side effects that aren't tolerated. It's important to understand "lines of treatment" and how they differ from first line treatment and can play a role in clinical trials.
What is a second line drug?
Second line drugs are the TB drugs that are used for the treatment of drug resistant TB. The second line drugs include levofloxacin, moxifloxacin and bedaquiline. There is also pretomanid which is a new second line drug recommended in 2019 for the treatment of drug resistant TB.
What is first line use?
First-line treatment or therapy simply refers to the initial, or first treatment recommended for a disease or illness. This may also be referred to as primary treatment, initial treatment, or induction therapy. With many conditions, including cancer, there are many possible treatments that could be effective.
[PDF] Target regimen profiles for TB treatment
Target regimen profiles for TB treatment apps who int/iris/bitstream/handle/10665/250044/9789241511339-eng pdf The optimal and minimal characteristics define a range: it is therefore expected resistant to the other oral first-line drugs isoniazid
[PDF] Chapter 6 Treatment of Tuberculosis Disease - CDC
Chapter 6 Treatment of Tuberculosis Disease - CDC www cdc gov/tb/education/corecurr/ pdf /chapter6 pdf (PZA) are considered first-line anti-TB drugs and form the core of Treatment completion is defined primarily as the ingestion of the total number of
[PDF] First-line tuberculosis treatment with double-dose rifampicin is well
First-line tuberculosis treatment with double-dose rifampicin is well research itg be/files/12944148/2020ijtl0499 pdf RIFAMPICIN (RMP R) IS THE CORE drug of first- line tuberculosis (TB) treatment regimens 1 Although for standard dose levels its early bactericidal activity
[PDF] Tuberculosis Drugs - Treatment Action Group
Tuberculosis Drugs - Treatment Action Group www treatmentactiongroup org/wp-content/uploads/2016/10/2016-Activists-Guide-to-TB-Drugs 1 5 pdf First-line agents: These drugs are used in the initial treatment of DS-TB Group A fluoroquinolones: These drugs are broad-spectrum antibiotics
[PDF] Classification of antituberculosis drugs: a new proposal based on
Classification of antituberculosis drugs: a new proposal based on erj ersjournals com/content/erj/46/4/887 full pdf This means not only high mortality but also First-line oral drugs: isoniazid rifampicin ethambutol pyrazinamide Group 2
[PDF] Goal of TB Treatment
Goal of TB Treatment tbcindia gov in/WriteReadData/l892s/8337437943TOG-Chapter 204-Treatment 20of 20TB 20Part 201 pdf more than one first-line anti-TB drug other than both INH and Rifampicin The drug has an extended half-life which means that it is still present in
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