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What happens when a muscle is inflamed?


Inflammation damages the muscle fibers, which causes weakness, and may affect the arteries and blood vessels that pass through muscle. Other symptoms include fatigue after walking or standing, frequent episodes of tripping or falling, and difficulty swallowing or breathing.

What is inflammation and how does it occur?

  • Inflammation is the body’s normal physiological response to injury. The cause of tissue injury is attributed to trauma, autoimmune, microbial, heat and toxins (chemicals). When tissue injury occurs, numerous substances are released by the injured tissues, which cause changes to the surrounding uninjured tissues.

What are the messengers of the inflammation process?

  • These substances are the messengers of the inflammation process, and have been viewed as areas of therapeutic intervention. Collectively they are called autocoids. Autocoids are substances released from the cells in response to various stimuli to elicit normal physiological responses locally.

What are the events of inflammation of the intestine?

  • Inflammation is characterized by the following events: 1. Vasodilatation of the local blood vessels 2. Increased capillary permeability (which causes an increase in interstitial fluid) 3. Clotting of the interstitial fluid (caused by fibrinogen) 4. Migration of monocytes and granulocytes 5.

What is the physiological response to tissue injury?

  • In Summary. In summary, the physiological response to tissue injury (trauma, infection, surgery, radiation, oxidative stress) involves both local and systemic reactions. The normal inflammatory response maintains homeostasis and allows for tissue healing. Chronic inflammation leads to multiple organ dysfunctions.
Although, the cause behind the inflammatory response is known. Inflammation occurs as a response to autoimmune cell damage; inflammation of the muscles destroys muscle tissue, and over time, can cause complete loss of muscle—called muscle atrophy. Inflammation can occur both internally and externally.