The basic procedure for performing a liquid-liquid extraction is to take two immiscible phases, one of which is usually water and the other of which is usually an organic solvent. The two phases are put into a device called a separatory funnel, and compounds in the system will distribute between the two phases.
One important application of a liquid–liquid extraction is the selective extraction of metal ions using an organic ligand. Unfortunately, many organic ligands are not very soluble in water or undergo hydrolysis or oxidation reactions in aqueous solutions.
Any one extraction operation gives rise to two product streams: the extracted feed solution, more usually termed the raffinate phase, and the solvent containing extracted solute termed the extract phase. This nomenclature is unique to liquid-liquid extraction processes and will be used from hereon.
For a simple liquid–liquid extraction the distribution ratio, D, and the partition coefficient, KD, are identical. (a) The fraction of solute that remains in the aqueous phase after the extraction is given by Equation . The fraction of solute in the organic phase is 1–0.400, or 0.600.