Does tau aggregation affect cognition and hippocampal atrophy?
Crary, J. F. et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol. 128, 755–766 (2014). Josephs, K. A. et al. Tau aggregation influences cognition and hippocampal atrophy in the absence of β-amyloid: a clinico-imaging-pathological study of primary age-related tauopathy (PART).
Does an elevated neocortical Tau PET signal predict cognitive decline?
Although an increased neocortical tau PET signal is rare in cognitively unimpaired individuals, even in amyloid-β-positive cases, such a signal holds important prognostic information because preliminary data suggest that an elevated tau PET signal predicts cognitive decline over time.
What does Tau pet tell us about neuronal injury?
Apart from assessing the degree of tauopathy, tau PET also provides information on neuronal injury, a pathological hallmark traditionally defined by regional hypometabolism on FDG-PET, increased total CSF tau, and cortical atrophy on structural imaging [ 30 ].
Does early-phase Tau pet correlate with FDG-PET hypometabolism in Alzheimer's disease patients?
It has been shown that early-phase (0–5 min p.i.) tau PET, which reflects cerebral blood perfusion, correlates well with FDG-PET hypometabolism in Alzheimer’s disease patients [ 34■, 35, 36 ], raising the possibility of optimizing one-stop shop protocols to enable noninvasive assessment of both tauopathy and neuronal injury in a single PET study.
Cours online de géophysique
PARTIE IV INTERPRETATION STRUCTURALE DES DONNEES DE SISMIQUE
Chapter 3 Neurotransmitter release
Chapter 2 Action potential
Physiologie humaine y compris éléments de neurophysiologie
LPSP1006
Introduction aux neurosciences cognitives
Neuropsychologie
Ray Tracing: intersection and shading
