A quartz crystal microbalance ( QCM) (also known as quartz microbalance (QMB), sometimes also as quartz crystal nanobalance (QCN)) measures a mass variation per unit area by measuring the change in frequency of a quartz crystal resonator.
"Studying Soft Interfaces with Shear Waves: Principles and Applications of the Quartz Crystal Microbalance (QCM)". Sensors . 21 (10): 3490-3573. Bibcode: 2021Senso..21.3490J. doi: 10.3390/s21103490.
where n is the overtone number and C is a constant that depends on the property of the crystal used. Equation 1, typically referred to as the Sauerbrey equation, constitutes the basic principle of QCM technology. 2 For a 5 MHz AT-cut quartz crystal at room temperature, C is approximately equal to 17.7 ng/ (cm 2 ·Hz).
A third approach that is gaining increasing popularity is QCM-D. In this method, the quartz crystal is excited to its resonance frequency for a short period by applying a driving voltage.