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Introduction to Radiation Biology

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  • What is the introduction of radiation?

    Simply put, radiation is the release of energy in the form of moving waves or streams of particles.
    This energy can be low-level, like microwaves and cell phones; or high-level, like X-rays or cosmic rays from outer space.
    These are known as non-ionizing and ionizing radiation.

  • What is the theory of radiation in biology?

    Radiation target theory refers to that ionizing radiation hits specific molecules or organellaes in cells, resulting in structural damage, gene mutation, chromosome breakage and other target effects of biological macromolecules.

  • What is the basic principle of radiation biology?

    The fundamental principles of radiobiology are repair, redistribution, reoxygenation, and repopulation.
    These are known as the “Four Rs” of radiobiology.
    The concept of split dose repair was operationally described by Elkind in the 1960s.

  • In conventional radiotherapy (RT), the relative biologic effectiveness of radiation is influenced by radiobiological determinants, the so-called '5Rs': Repair, Repopulation, Redistribution, Reoxygenation, and Radiosensitivity.
Radiobiology explores the biological effects of radiations. This research field was created following the description of the first cases of cutaneous erythema associated with the clinical use of radiation at the beginning of the twentieth century.

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Introduction to Radiation Biology