Simply put, radiation is the release of energy in the form of moving waves or streams of particles.
This energy can be low-level, like microwaves and cell phones; or high-level, like X-rays or cosmic rays from outer space.
These are known as non-ionizing and ionizing radiation.
Radiation target theory refers to that ionizing radiation hits specific molecules or organellaes in cells, resulting in structural damage, gene mutation, chromosome breakage and other target effects of biological macromolecules.
The fundamental principles of radiobiology are repair, redistribution, reoxygenation, and repopulation.
These are known as the “Four Rs” of radiobiology.
The concept of split dose repair was operationally described by Elkind in the 1960s.