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Chronic inflammatory demyelinating polyneuropathy and diabetes

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  • Can diabetes cause demyelination?

    found a significantly higher occurrence of demyelinating neuropathy meeting the electrophysiologic criteria for CIDP in types 1 and 2 DM patients (32/189 DM patients, 16.9 %), than in nondiabetic patients (17/938 patients, 1.8 %), with a calculated odds of occurrence 11 times higher among diabetic than nondiabetic

  • Is polyneuropathy related to diabetes?

    Diabetic polyneuropathy (DPN) affects multiple peripheral sensory and motor nerves that branch out from the spinal cord into the arms, hands, legs and feet.
    Typically, the longest nerves — those that extend from the spine to the feet — are affected the most.

  • What to avoid with CIDP?

    Reduce your intake of red meat by eating more lean poultry and fish (including at least one portion of oily fish per week) and replacing or supplementing meat with lentils, pulses and beans.
    Strictly limit fats, sugar, alcohol and processed meats.

  • In general, CIDP disease life expectancy for patients is comparable to that of healthy counterparts, however, the quality of life may be significantly impacted.
    Quadriplegia (paralysis of the arms and legs), respiratory failure, and death rarely occur.
CIDP is the most common and treatable inflammatory neuropathy that occurs in patients with diabetes. The main first-line therapies are intravenous immunoglobulin (IVIg) or corticosteroids, and their use is based on the knowledge that CIDP results from aberrant immune responses to peripheral nerve antigens (Fig. 3).

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Chronic inflammatory demyelinating polyneuropathy and diabetes