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BCR/ABL (ABL1) Translocation Dual Fusion Probe

What is a vysis BCR/ABL1 tri-color DF fish Probe kit?
For more information, contact Abbott. The Vysis BCR/ABL1/ASS1 Tri-Color DF FISH Probe Kit is intended to detect the t (9;22) (q34;q11.2) reciprocal translocation involving the BCR and ABL1 gene regions using the fluorescence in situ hybridization (FISH) technique.
What chromosomes do vysis LSI bcr/abl fusion probes hybridize to?
For more information, contact Abbott. Vysis LSI BCR/ABL Dual Color Dual Fusion Probes hybridize to chromosome 22q11.2 (breakpoint cluster region SpectrumGreen) and to chromosome 9q34 (abl oncogene SpectrumOrange). The hybridized probe fluoresces with moderate to bright intensity both in interphase nuclei and on metaphase chromosomes.
What is the tri-color design of a BCR/ABL1 fusion test?
The Tri-Color design of this test uses a probe in a third color (aqua) on the centromeric side of the ABL1 breakpoint, which co-localizes with the orange signal in a random orange/green signal fusion, but is absent from a true BCR/ABL1 molecular fusion on the der (22) chromosome.
Does BCR/ABL1 fusion have a cytogenetically normal chromosome 9?
Real-time polymerase chain reaction revealed the presence of the typical e14a2 (b3a2, M-BCR) fusion transcript. However, fluorescence in situ hybridization (FISH) analysis using dual-color, dual-fusion probes for BCR/ABL1 showed only 1 BCR/ABL1 fusion, present on a cytogenetically normal chromosome 9, associated with diminished ABL1 signal.

What is a vysis BCR/ABL1 tri-color DF fish Probe kit?