Systems biology of personalized nutrition - Oxford Academic
academic oup com/nutritionreviews/article- pdf /75/8/579/24349956/nux029 pdf
Personalized nutrition tailors dietary recommen- dations to specific biological requirements on the basis of a person's health status and goals The biology
NUTRITION AND HEALTH - NIOS
nios ac in/media/documents/SrSec314NewE/Lesson-28 pdf
Nutrition and Health BIOLOGY 242 Notes MODULE - 4 Environment and Health Food is the basic necessity of life We all know that regular supply of food
The evolution of human nutrition - Cell Press
www cell com/current-biology/ pdf /S0960-9822(13)00363-1 pdf
But what does this mean in terms of biological adaptation? Is there a particular kind of food item, or combination of items, that humans need to thrive? Also,
food-technology-and-therapeutic-nutrition-in-the-biology-textbooks
www ejmste com/download/food-technology-and-therapeutic-nutrition-in-the-biology-textbooks-of-the-intermediate-stage-5601 pdf
The method of content analysis has been adopted to accomplish the paper aim The results show that the biology textbook (Human being and Health) for the third
The Science and Lore of Healthy Eating - Evidence Analysis Library
www andeal org/vault/2440/web/Umami_Science_and_Lore_of_Health_Eating_201708 pdf
We know eating a balanced diet with plenty of fruits and vegetables is good for our health But, what if you don't like the taste of those foods, even though
How to strengthen the link between biology and implementation for
humanhealth iaea org/HHW/Nutrition/Symposium2018/presentations/14 1 Emorn pdf
require composite knowledge of biology plus nutrition, food, social, behavioral, implementation sciences etc • Policy and Program Advocacy
32128_714_1_Emorn.pdf
EmornUdomkesmalee
Institute of Nutrition, MahidolUniversity
Thailand
How to strengthen the link between
biology and implementation for sustainable action
Evidence for Implementation
•require composite knowledge of biology plus nutrition, food, social, behavioral, implementation sciences etc •Policy and Program Advocacy Good nutrition for maternal health, child development espBRAIN, work capacity, prevention of disabilities and diseases, longevity + quality of life
Investing in nutrition -economic benefits
•Targeting and timing of intervention •Program design -Proven effective intervention •Monitoring -Progress, Feedback for Adjustment •Impact evaluation
Era of Nutrition Research
•1920-1950 Vitamin discovery/deficiency diseases; nutrient focus strategies ;RDAs •1950-1970 Staple calories; caution-fat; protein- enriched formulas •1970-1990Address hunger/micronutrient def- supplementation and fortification •1990-2010 Double burden of malnutrition-rapid rise of obesity/NCDs in LMICs; dietary patterns for chronic diseases •FUTUREComplexities of diet and health; food quality focus; modern agriculture, food processing and innovation-optimal diet patterns
Source: D MozaffarianBMJ 2018
Food Systems Are Central to Diets & Human Health
HLPE Report 2017
P. Winichagoon, INMU
Short-term and long-term effects
of undernutrition
Short-term
Long-term
Brain development
Cognitive & education
performance
Growth&muscle mass
Body composition
Immunity
Work capacity
Metabolic
Programming of
glucose, lipids, protein hormone/receptor/gene
Diabetes, Obesity,
Heart disease, high
blood pressure, cancer, stroke and ageing
Early
nutrition in utero and childhood Source: ENDING MALNUTRITION BY 2020:AN AGENDA FOR CHANGE IN MILLENNIUM of the SCN
Commission on Nutrition, February
2000. (FNB 2000)
The Lancet'sSeries on Maternal and Child
Undernutrition 2008
KEY MESSAGES
Key Messages (Lancet 2008)
Undernutrition: stunting, wasting, IUGR3.6 mil child deaths, 11% disease burden
Stunting in first 2 yrs-irreversible damage; rapid wtgain after undernutr-increase risk of NCDs as adults
Proven effective interventions to reduce stunting and MN def: breastfeeding/CF, VA and Zn suppln; mgtof severe malnutrition
Crucial period: conception to 2 yrold or 1,000 days window Greater natlpriority; intersectoralapproaches; better coordination in the global nutrition system
Lifecycle: the proposed
causal links
Higher
maternal mortality Reduced mental capacity Reduced capacity to care for baby
Inadequate
foetal nutritionHigher mortality rate
Impaired mental
development
Untimely / inadequate
Weaning
Frequent
infections
Inadequate food,
health & care
Inadequate
growth Woman
Malnourished
Pregnancy
Low Weight
Gain
Adolescent
Stunted
Child
Stunted
Elderly
Malnourished
Baby
Low Birth
Weight
Inadequate food,
health & care
Inadequate food,
health & care Reduced mental capacity Inadequate food, health & care
Epigenetic
susceptibility to chronic diseases if diet becomes inappropriate
Adapted from James et al. SCN
Millennium Rep. Food &
Nutrition Bulletin, 2000, 21, 3S.
The Lancet Maternal and Child Nutrition Series 2013
Lancet Maternal/Child Nutrition Series 2013
P. Winichagoon, INMU
'
1000 Days': The Window of
Opportunity--DOUBLE DUTY
intervention
ConceptionChild birth2-yrs old
age
P. Winichagoon, INMU
Target groups
Pregnant women
0-6 moold infants6-24 moold children
Strategy
Integrated health and social activities by local government and participation of stakeholders
Integrated package:
nutrition, play, child development, dental hygiene, water, sanitation, etcANC, WCC and family well-being through local
H and MCH
board
Committee on
quality of life at district level -Hlth/
Social
protection/Ed /Interior
Achievements
: Optimal growth (height) & development
CONCEPT & STRATEGY
P. Winichagoon, INMU
Menu of activities for 1000 days
Health
functionary
Pregnant womenLactation0-6 moinfants
6-24 mo
At ANC:
Monitor pregwt
gain-GWG graph
Assess -counsel
-demonstrate diets
Iron-folate-iodine
supplement throughout preg
Services for lactating mothers:
Reviving 10-step for successful BF
Enforce code of marketing for
infant formula
Counsel on breastfeeding/ diets
during lactation
Provide iron/folate/iodine
supplement
Demonstrate: diets for lactating
women
Counsel -
diets for 1-
2 y old
weekly
iron suppl.
Assessing child growth and development
Assessing child eating (dietary diversity)
Demonstrate: preparation of child diets
Counsel & demonstrate to mothers on monitoring & interpretation of child growth
Courtesy: Prof. Yap-Seng Chong, TCN Oct 2018
Courtesy: Prof Yap-Seng Chong, TCN Oct 2018
Courtesy: Prof Yap-Seng Chong, TCN Oct 2018
Courtesy: Prof Yap-Seng Chong, TCN Oct 2018
Strengthen Biology -Implementation
•Type and quality matters-The BEST of Science drives Policy-endorsed by international experts
•Existing international events global gatherings as dialogue platform for knowledge sharing and interactive discussion
•strategic communication-insights on national policy/program decision and PRIORITY area •translation of advanced biological evidence for effective interventions •identification of 'entry point' for dialogue-building trust •proposing model of collaboration to speed up achievement of committed goals.