CHAPTER 128 System ic Im m unom odulators Fig 128 3 Erythematous edematous plaque at the site of GM-CSF injection Fig 128 4 Mechanism of action of the
Fitzpatrick's Dermatology in General Medicine, 6th ed edited by Irwin M Freedberg, Bolognia's Dermatology, Fitz has Early chapters in the book in-
Studying during dermatology residency may be overwhelming due to chapters alongside more active learning measures, such TABLE 1 as “Bolognia”)
CHAPTER 0 Basic Principles of Derm atology Table 0 1 Primary lesions – morphological terms Some of the photos courtesy, Jean L Bolognia, MD;
variety of financial topics that dermatology Bolognia, Jean, Joseph Jorizzo, and Julie Schaffer “Chapter 57 ”Dermatology 3rd ed
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Neoplastic
Dermatologic
disorders N o n -in fe c t io u s I n f l a m m a t o r y I n f e c t i o u s O t h e r
ViralBacterialFungal
ProtozoalMalignant
Autoimmune
bullous diseasesAutoimmune connective tissue diseasesPapulosquamous and eczematous dermatoses
Urticarias and
erythemasMetabolic and toxic insults/trauma
Genodermatoses
and developmental anomaliesCLASSIFICATION SCHEME FuOR DERMATOLOGIC DISORDEuRS
Benign
Non-palpable
FibrosisNests of
nevus cells
Epidermal
Palpable
Dermal
Soft or depressed
Dermal atrophy Lipo-
atrophy
MAJOR TYPES OF CUTdANEOUS ATROPHY
Epidermal
Subcutaneous (lipoatrdophy)Dermal
Lichen sclerosusStriaeLupus panniculitis
Pressure
LINEAR CONFIGURATImON PATTERNS
Linear configuratihon patterns
Trauma/exposure ("outmside job")
Excoriations due tho
scratchingAcute allergic conthact dermatitis to poisohn ivySporotrichoid patternm
Atypical mycobacterihal
infectionDermatomal
Herpes
zosterSegmental neurofibromatosis
Koebner phenomenon
Lichen planusAlong lines of Blasmchko
Epidermal nevusOther
Linea nigra Papular mucinosis
ವ ವ ವ ವ ವ ವ ವ Approach to the pastient with an acutse fever and a "rashs" *
Kawasaki
diseaseInfectious e.g. toxic shock syndromes; SSSS; scarlet fever; septic emboli (
Meningococcus,
Rickettsia
> other bacteria); secondarry syphilis; disseminarted erythema migransBacteria e.g. exanthems due rto enteroviruses, HHV-6r, adenovirus (see Fig. 81.2), HIrV; varicella, disseminated zosterr ** ;
Kaposi varicelliform
eruptionViruses Fungi ** e.g. disseminated dimorphic infection
Protozoa
** e.g. StrongyloidiasirsInflammatory
Morbilliform, serum
sickness-like reactrion,
DRESS, AGEP,
erythrodermaDrug reactions ***
Primary cutaneous
disorders (e.g. pustular psorirasis)
Rheumatologic
disorders (e.g. SLE, vasculitirs,
Still disease)Erythema multiforme,
SJS/TEN
Graft-versus-host
diseaseOther
Neoplastic
(e.g. lymphoma)Inherited (e.g. periodic fever syndromes) ****** not a single site ars in cellulitis, necrrotizing fasciitis more likely in immunorcompromised patient
early on, more seriousr drug reactions, e.gr. DRESS, may resemble ra morbilliform eruptiorn APPROACH TO THE PATsIENT WITH AN ACUTE sFEVER AND A "RASH"
DIFFERENT CUTANEOU
S BIOPSY TECHNIQUE
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