4 août 2017 · In contrast to G1 and G2, cell cycle progression in S phase is Unlike during G1, when temporary arrest was never a predominant outcome
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of the cell-cycle checkpoint responses of mammalian cells to Opinion in Cell Biology Maintenance of the G1/S arrest after DNA damage is a delayed
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1 mar 1997 · G1 checkpoint arrest (Ko and Prives, 1996; Sherr, The primary cellular event in this phase is activation of
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irradiation in the different phases of the cell cycle under the rubric of a single checkpoint activated by damage in the DNA (Elledge, 1996;
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activates checkpoints that delay cell-cycle progression and trigger DNA repair different times during a given cell-cycle phase, DNA damage checkpoint
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Cells that have incurred DNA double-strand breaks (dsbs) during G1 phase activate p53 primarily via an ATM-de- pendent pathway In cells that express both ATM
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