[PDF] safety assessment of glycerin as used in cosmetics

What is the role of glycerin in cosmetics?

Glycerin is reported to function in cosmetics as a denaturant, fragrance ingredient, hair conditioning agent, humectant, oral care agent, oral health-care drug, skin protectant, skin condi- tioning agent—humectant, and viscosity-decreasing agent. Impurities were reported to be water, polyglycerol, and diethylene glycol.

Is glycerin safe?

ered generally recognized as safe (GRAS) by the FDA for its use in food packaging and it is a multiple-purpose GRAS food substance when used in accordance with good manufacturing practices [21CFR182.90; 21CFR182.1320]. Also, glycerin is approved for use in over-the-counter drugs, such as anorectal

What are glycerin ethoxylates used for?

The glycerin ethoxylates are primarily are used widely in a variety of rinse-off and leave-on cosmetics products, and most of these reported uses are in some type of hair or skin cleansing formulations. Glycereth-26 has the highest reported frequency of use (379 formulations), and Glycereth-7 has the second greatest reported number of uses (80).

How does glycerin affect plasma glyceride concentration?

Acute ingestion of glycerin (1 mL/kg in water) in human male patients led to an increase in plasma glycerides. In human female patients, the oral administration of glycerin (1 mL/kg in water) resulted in no change in plasma glyceride concentra- tions. When glycerin (1 mL/kg/d in 3 doses) was orally admi-