[PDF] chemical properties of amides pdf

Is amide a basic compound?

Amides are neutral compounds -- in contrast to their seemingly close relatives, the amines, which are basic. The amide linkage is planar -- even though we normally show the C-N connected by a single bond, which should provide free rotation. Figure 1 below shows this common drawing of an amide. Figure 1. An amide; usual representation.

What chemical reactions do amides undergo?

Amides undergo many chemical reactions, although they are less reactive than esters. Amides hydrolyse in hot alkali as well as in strong acidic conditions. Acidic conditions yield the carboxylic acid and the ammonium ion while basic hydrolysis yield the carboxylate ion and ammonia.

Which amide produces an organic acid and ammonia?

The hydrolysis of a simple amide produces an organic acid and ammonia. Butanamide thus yields butanoic acid and ammonia. The hydrolysis of an amide produces an organic acid and ammonia. Benzamide thus yields benzoic acid and ammonia. Write the equation for the hydrolysis of each compound.

What is the difference between amines and amides?

Compared to amines, amides are very weak bases. While the conjugate acid of an amine has a p Ka of about 9.5, the conjugate acid of an amide has a p Ka around ?0.5. Therefore, amides don't have as clearly noticeable acid–base properties in water.