[PDF] Determination of Coronary Flow Reserve - Circulation

Klocke FJ: Measurements of coronary flow reserve: Defining pathophysiology versus making decisions about patient care. Circulation 1987;76:1183-1189. 9  Autres questions
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  • How do you measure coronary flow reserve?

    There are two popular methods to measure coronary flow reserve.
    One is an invasive method that requires a cardiac catheterization of your coronary artery.
    Another is a noninvasive method that uses a specific type of nuclear stress test — a Rubidium-82 positron emission tomography (PET).

  • What are the determinants of coronary circulation?

    The two major determinants of coronary flow are coronary arterial pressure and myocardial oxygen consumption.
    At constant oxygen consumption, coronary flow is relatively independent of arterial pressure which is referred to as coronary autoregulation.

  • What is R1 R2 R3 in coronary circulation?

    Blood flow has 3 major resistance components: the epicardial vessel (R1), the small arteries and arterioles (R2), and the intramyocardial capillary system (R3).
    When coronary reserve is normal, these 3 resistances are assumed to be functioning normally.

  • What is R1 R2 R3 in coronary circulation?

    FFR is a ratio of coronary and aortic pressures characterizing epicardial conductance.
    In the other hand, CFR assesses both the epicardial and microvascular compartments and is defined as the ratio between hyperemic and resting flows.

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