[PDF] axial spondyloarthritis vs ankylosing spondylitis

To clear things up, Ankylosing Spondylitis (AS) is actually the same as Axial Spondyloarthritis (AxSpA), but only one of the 2 subgroups of AxSpA. AS is known as radiographic AxSpA, whereas the other subgroup is known as non-radiographic.
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  • What is difference between spondylitis and ankylosing spondylitis?

    The inflammatory or ankylosing spondylitis can cause weaker bones and sometimes lead to osteoporosis. Spondylitis affects the lumber spine (lower back) and sacroiliac joints, but in peripheral spondylitis, the joints farther from the spine, such as hands and feet, are involved.

  • What is axial spondyloarthritis?

    Axial spondyloarthritis (axSpA) is a type of arthritis that affects the joints in your axial skeleton (chest, spine and pelvis). People with axSpA often have back pain before the age of 45 and may even have stiffness and pain as teens or young adults. This pain can be severe and debilitating.

  • Do patients with non radiographic axial spondyloarthritis differ from patients with ankylosing spondylitis?

    There are some differences in AS and nr-axSpA: the male to female ratio in AS is roughly 3:1, whereas in nr-axSpA it is 1:1. In nr-axSpA the frequency of HLA-B27 is lower, and the C-reactive protein level may be normal compared to AS patients. The management of nr-axSpA is very similar to that of AS.
  • HLA-B27 contributes to approximately thirty percent of the heritability of ankylosing spondylitis. [2] The incidence of acute anterior uveitis in HLA-B27 positive patients has shown on meta-analysis to vary from 40 to 82.5%. It can precede the onset of ankylosing spondylitis by approximately three years.
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