[PDF] acetic acid and salicylic acid reaction

To make acetylsalicylic acid, the -OH group of the salicylic acid reacts with acetic acid to produce the ester and water. This reaction, like most esterification reactions, is an equilibrium process that does not go to completion and will not produce 100% yield unless the water is removed during the reaction.
View PDF Document


  • What type of reaction occurs between salicylic acid and acetic acid?

    One of the most common examples of an acetylation reaction is the acetylation of salicylic acid with acetic anhydride to afford acetic acid and acetylsalicylic acid as the products.

  • What happens when salicylic acid is mixed with acetic anhydride?

    Aspirin can be made in the laboratory by reacting acetic anhydride (C4H6O3) with salicylic acid (C7H6O3) to form aspirin (C9H8O4) and acetic acid (C2H4O2).

  • What is acetic salicylic acid?

    Acetylsalicylic acid commonly known as Aspirin is a prototypical analgesic with the chemical formula C9H8O4. It is also known as aspirin or 2-Acetoxybenzoic acid. It appears as a crystalline powder which is colourless to white.
  • SALICYLIC ACID is a carboxylic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic.
View PDF Document




1 University of Wisconsin Chemistry 116 Preparation and

salicylic acid reacts with acetic acid to produce the ester and water. This reaction like most esterification reactions



Experiment 8 – Synthesis of Aspirin

(acetylsalicylic acid also known as aspirin) was shown to be much less Aspirin can be made by reacting salicylic acid with acetic acid in the presence ...



Experiment 5 - Synthesis of Aspirin

In the presence of moisture aspirin may decompose (hydrolysis) into salicylic acid and acetic acid. This reaction is the reverse of the synthesis reaction. The 



Chapter 5 Carboxylic Acids and Esters

Learn the major chemical reaction of carboxylic acids and esters and learn how to Produced by reacting salicylic acid with acetic.



The Synthesis of a Medicinal Agent- Aspirin By Walter Scharf and

It was eventually discovered that salicylic acid is the portion of these complete reaction in the preparation of an acetate ester is to use acetic.



Ester Synthesis Lab (Student Handout)

Esters are produced by the reaction between alcohols and carboxylic acids. For example reacting ethanol with acetic acid to give ethyl acetate is shown 



Colorimetric Determination of Iron with Salicylic Acid

the effects of diverse ions. THE reaction between salicylic acid and ferric ion in acetic acid solution to give an amethyst coloration has.



Percent Yields from Reactions

Salicylic acid reacts with acetic anhydride to form aspirin acetylsalicylic acid. If the percent yield in this reaction is 78.5%



Practical Lab Manual of Pharmaceutical Organic Chemistry - II

Salicylic Acid by Nitration Reaction . Insoluble in water and soluble in 85 % acetic acid and ethanol. 3. Boiling point is about 117 oC.



Separation of Salicylic Acid Impurities with Different Acid Mobile

acetic acid change the selectivity of the separation of sal- It is acidified to give the desired salicylic acid. The main reaction is shown in Figure 1; ...