During the catalytic cycle, an alcohol is dehydrogenated to the corresponding carbonyl compound, which reacts with the amine to form an imine The imine is in situ reduced to the alkylated amine and the metal complex facilitates the required hydrogen shuttling
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are more acidic than neutral water/alcohol 5 Neutral amine can completely deprotonate carboxylic acids, but not water or alcohols 6 Therefore hydroxide can
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14 oct 2011 · [19, 23] Here, the alcohol is activated by oxidation to give an aldehyde or ketone, which then undergoes a condensation reaction with the amine
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