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preparations The formation of granulation tissue in the skin has been noted from the use of both etretinate and isotretinoin



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patients who are not pregnant, because Accutane can cause severe birth defects (see Boxed There is some evidence that long-term, high-dose, or multiple



[PDF] Possible long term teratogenic effect of isotretinoin in pregnancy

This agent has severe teratogenic effects, as serious craniofacial, cardiovascular, thymic and central nervous system malformations The baseline population risk of malformations is 3-5 , but it increases to almost 30 in women exposed to isotretinoin during the first trimester of pregnan- cy



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Side Effects ▫ Efficacy long-term impacts on the human throat and gut microbiome PLoS ONE acne patients treated with isotretinoin: a systematic review



[PDF] Preventing and Managing the Side Effects of Isotretinoin - Zenodo

should not be taking isotretinoin 8 Isotretinoin does not have long-term effects on fertility, and there have been no cases of retinoid malformations in children of 



[PDF] ISOTRETINOIN - MALE - British Association of Dermatologists

and occasionally, a prolonged or second course of treatment is required In general the side effects of isotretinoin are mild and settle later in the course

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