PDF 42-1-15.pdf

When maintained under dry conditions, the compound is very stable at room temperature (1) However, at elevated tempera- tures and in the presence of trace moisture, acetaminophen degrades more rapidly to p-aminophenol, which subsequently undergoes additional oxidative changes (1,5,6)

Chemical stability was confirmed, with paracetamol content in the tablets within the British Pharmacopoeial range of 95 to 105 of the labelled amount

[PDF] Paracetamol - CPY Document

IARC MONOGRAHS VOLUME 50 (e) Stability Dry, pure paracetamol is stable to 45°C Contamination with traces of para-aminophenol, and humid conditions

[PDF] A pH Study for the Degradation of Acetaminophen with Iron - AIDIC

In particular, for water splitting experiments they are used in a solution of KOH or NaOH with pH 14 since their chemical stability is ensured (Rangaraju et al , 2009

Acetaminophen - ScienceDirectcom

appears to be acid catalyzed and base catalyzed 14, 15 Maximum stability is seen at pH 5-6 14 USP XIX requires that acetaminophen tablets diSintegrate in 30

[PDF] STABILITY OF PARACETAMOL IN PACKAGED TABLET

Paracetamol degradation in tablets follows apparent first-order kinetics and the shelf-lives (t90) range from 9 8 to 23 0 months PVC/PVDC/AI foil and polycoated

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[PDF] Stability of Paracetamol Tablets Repackaged in Dose - CORE

[PDF] Paracetamol - CPY Document

[PDF] A pH Study for the Degradation of Acetaminophen with Iron - AIDIC

Acetaminophen - ScienceDirectcom

[PDF] STABILITY OF PARACETAMOL IN PACKAGED TABLET