[PDF] Isotonicity - Mathcentre
pharmacy, isotonicity calculations are most often performed for parenteral and ophthalmic solutions which must have a freezing point depression of 0 52◦C for
Rapid Method for Calculating Isotonic Solutions - ScienceDirectcom
lowering of the freezing point is known for aque- ous solutions, it is possible to calculate the molal concentration of a particular substance required for isotonicity
[PDF] Tonicity Calculations: An Aid to Understanding
22 jan 2018 · examples will be reported Keywords: Isotonicity; Pharmaceutical calculation; Colligative properties Introduction The tonicity of a solution may
[PDF] Methods of adjusting tonicity and pH values of some drugs and
Sodium chloride equivalent method PSA = 0 9 – (PSM E of medicament) Where, PSM = Percent strength of medicament PSA = Percent of sodium chloride for adjustment of isotonicity Above equation is used to calculate the amount of adjusting substance (sodium chloride) required for making the solution isotonic
[PDF] Isotonic and Buffer Solutions
Calculations of Tonicic Agent Required The procedure for the calculation of isotonic solutions with sodium chloride equivalents may be outlined as follows:
[PDF] Methods of adjustment of Isotonicity 1 Freezing - SNS Courseware
solutions having freezing point at -0 52°C will be isotonic with blood plasma as one can calculate the quantity by multiplying the freezing point with the factor
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