role vitamine b12

B12 & Cobalamin - JSMU

Vitamin B12 Stores • Normal body stores of vitamin B12 about 3-4 mg, primarily in liver • This would be sufficient for 3 years if dietary intake ceased or if the ability to absorb the vitamin was lost Plants are not sources of Vit B12 Vitamin B12; Dietary requirement • Recommended intake (RDA) 3μg/day • 6μg/day in pregnancy & Lactation

The Coenzyme Forms of Vitamin B12: To- ward an Understanding

The Coenzyme Forms of Vitamin B12: To-ward an Understanding of their Therapeutic Potential Gregory Kelly, N D Abstract Although cyanocobalamin and hydroxycobalamin are the most commonly encountered supplemental forms of vitamin B12, adenosyl- and methylcobalamin are the primary forms of vitamin B12 in the human body, and are the metabolically

Vitamin B12 for the treatment of vasoplegia in cardiac

vitamin B12 (V-B12), is approved by the U S Food and Drug Administration for the treatment of cyanide (CN) poisoning (by smoke inhalation) 1-4 Vitamin B12 is also known to prevent the development of pernicious anemia and is important in the production of many heme-containing cytochromes as well as DNA 5 Its ‘‘off-label’’

Journal of Hematology & Thromboembolic Diseases

Vitamin B12 is an essential cofactor required for biochemical pathways involved in DNA/RNA synthesis and fatty acid metabolism [4] The role of vitamin B12 in DNA/RNA synthesis is in the regeneration of tetrahydrofolate and conversion of homocysteine to methionine [4] As these two processes are joined, such that

The Role for Vitamin and Mineral Supplements in Diabetes

48 Sun Y, Lai MS, Lu CJ Effectiveness of vitamin B12 on diabetic neuropathy: systematic review of clinical controlled trials Acta Neurol Taiwan 2005; 14: 48-54 49 Talaei A, Siavash M, Majidi H, Chehrei A Vitamin B12 may be more effective than nortriptyline in improving painful diabetic neuropathy Int J Food Sci Nutr 2009; 60 Suppl 5: 71

Conclusions of a WHO Technical Consultation on folate and

acid and vitamin B 12 in synthetic form are absorbed at about twice the efficiency as the food forms, especially in lower doses The consultation agreed on conclusions in four areas: » Indicators for assessing the prevalence of folate and vitamin B 12 deficiencies » Health consequences of folate and vitamin B 12 defi-ciencies