Comparison of microbial challenge testing methods for cosmetics
procedure for the challenge test Alongside the test from the EU (2) and US pharmacopoeia (3), the Personal Care Products Council (4), the ASEAN Cosmetics Association (5), in-house test protocols (6, 7) have been established for many years A new method, the first edition of ISO 11930 was published in April 2012 under the title Cosmetics -
PRESERVATIVE EFFECTIVENESS TESTING
• Other Challenge Test Methods o AOAC 998 10 Preservative Challenge Efficacy Test of Non-Eye Area Water Miscible Products o ISO 11930 Efficacy Test and Evaluation of Preservation of a Cosmetic Product
Microbiological Stability of Cosmetics by using Challenge
cosmetic industry is the Challenge Test (Brannan et al , 1997; UNI EN ISO 11930:2012; Siegert, 2010, 2013) This method reproduces at laboratory scale the microbial aggression that a product can undergo during manufacture, storage and use allowing to evaluate cosmetic antimicrobial protection The aim of the work was to compare the antimicrobial
The Challenge Test Laboratory
Challenge Test PET, Preservation Efficacy Test, EP, USP, ISO 11930, Mixed Culture, Recontamination Patch Test Irritation Allergens Fragrances, Extracts Traces - Impurities Preservatives, UV Filters, Vitamins, Heavy Metals Formaldehyde, Migration Residues, Colorants Safety Assessment Stability Accelerated Ageing +50°C, +20°C, RT, +40°, UV-VIS
ECOLOGICAL OPTIMISATION WILL BE THE KEY
Hydrolat Additive TAMC TYMC Challenge test, ISO 11930 Cedrus atlantica (Cedar) bark water – > 1000 > 1000 Failed Citrus aurantium amara (Neroli) flower water – > 1000 > 1000 Passed (B) Rosa damascena (Rose) flower water – > 1000 > 1000 Failed Hydra-Leen 5 Rose Pentylene Glycol < 10 < 10 Passed (A) Hydra-Leen 8 Rose Caprylyl Glycol
Cosmetic Preservative Efficacy Testing - MSL
method EP5 1 3 Preservative Efficacy Test (Pharma Challenge Test) is often employed, as it is a more stringent method It should be noted that factory isolates should also be included in the Challenge test to ensure that the preservative system is effective on the microorganisms that are likely to be introduced during the production process
[PDF] challenge test protocole
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