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Antimicrobial-Resistant Phenotype Definitions

Phenotype Name Phenotype Code Phenotype Definition Methicillin-resistant Staphylococcus aureus MRSA_HAI Staphylococcus aureus that has tested Resistant (R) to at least 1 of the following: methicillin, oxacillin, or cefoxitin Carbapenem-resistant Enterobacteriaceae CREall_HAI Any



AR Option Phenotypes

Phenotype Name Phenotype Code Phenotype Definition Carbapenem-non-susceptible Pseudomonas aeruginosa carbNS_PA_AR Pseudomonas aeruginosa that has tested either Intermediate (I) or Resistant (R) to at least one of the following: imipenem, meropenem, or doripenem Extended-spectrum cephalosporin-resistant E coli ESCecoli_AR Any



Asthma Phenotypes: Clinical Implications

Definition of Phenotype •The observable properties of an organism that are produced by the interaction of the genotype (genetic make-up) and the environment •As applied to asthma, refers to subtypes of asthma, typically with unique triggers or symptoms •Uncertain whether some asthma phenotypes are actually different



OHDSI Cohort Definition and Phenotyping

• A phenotype is a way to represent a person with a condition or exposure using data in an electronic health record • Thus phenotypes are an important foundation of describing the methods of an observational research study



Defining Phenotypes: Expanding Our Understanding of Asthma

Feb 28, 2007 · Phenotype in each category at age 6 years N =826 Significant risk factors for each phenotype MD dxed asthma age 6 years dxed with bronchitis age 6 yrs Skin test positive age 6 yrs Never Wheezed 51 5 Reference Group-- -- 33 8 Transient Early Wheezers 19 9 Maternal smoke exposure-- -- 38 4 Late-onset Wheezers 15 •Rhinitis apart



Molecular Phenotypes - University of Delaware

One definition of a gene is that it is the information to make one specific product, with the different alleles of the gene producing different versions of that product The first gene products to be studied were enzymes and the greatest interest was in their activity, that is, the reactions they catalyzed



Johns Hopkins Medicine, based in Baltimore, Maryland

phenotype identifies a subset at high risk Of the adverse health outcomes clinically associated with frailty To do this, we operationalized a definition Of frailty, as suggested by prior research and clinical consensus (Figure l), and, in a popula- tion-based study Of Older adults, evaluated its prevalence



Frailty in Older Adults: Evidence for a Phenotype

phenotype identifies a subset at high risk of the adverse health outcomes clinically associated with frailty To do this, we operationalized a definition of frailty, as suggested by prior research and clinical consensus (Figure 1), and, in a popula­ tion-based study of older adults, evaluated its prevalence

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