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SCCP/1171/08

8 июн. 2012 г. 1. Does the SCCS/SCHER/SCENIHR consider the TTC approach appropriate for the human health risk assessment of chemical substances? 2. In ...



the sccs notes of guidance for the testing of cosmetic ingredients

extend/ refine the TTC framework (e.g. for inhalation TTC and internal TTC) the SCCS considers that at present the thresholds proposed by Yang et al 



the sccs notes of guidance for the testing of cosmetic ingredients

extend/ refine the TTC framework (e.g. for inhalation TTC and internal TTC) the SCCS considers that at present the thresholds proposed by Yang et al 



Scientific Committee on Consumer Safety SCCS OPINION on

21 мар. 2023 г. - The Applicant used TTC approach to justify the safety of sodium bromothymol blue but the SCCS estimate of the SED indicates that it exceeds ...



Scientific Committee on Consumer Safety (SCCS) Meeting of the

14 сент. 2022 г. It was stressed that safety assessment of the annexed substances should not be limited to the use of TTC alone but in combination with ...



The Threshold of Toxicological Concern (TTC) is a Pragmatic Risk

The TTC is based on the principle of establishing a human exposure threshold [3] SCCS (2014). Scientific Opinion on Basic Blue 124. SCCS/1542/14. [4] SCCS ...



THE SCCS NOTES OF GUIDANCE FOR THE TESTING OF

Keywords: SCCS SCCS Notes of Guidance for the Testing of Cosmetic Ingredients and their TTC value as if the TTC value is also an internal exposure value.



Scientific Committee on Consumer Safety (SCCS) Meeting of the

12 мар. 2019 г. This was a closed scientific workshop on SCCS invitation only. All ... TTC is a concept allowing under specific conditions



SCIENTIFIC ADVICE on HC Blue 18 (Colipa No. B122) Submission II

27 апр. 2023 г. Based on the TTC assessment of Impurity 3B the calculated SED values are below the (external) TTC. Taken from SCCS/1560/15. SCCS comment. The ...



ADMIN SCCS Notes of Guidance for the Testing of Cosmetic

18 авг. 2023 г. extend/ refine the TTC framework (e.g. for inhalation TTC and internal TTC) the SCCS considers that at present the thresholds proposed by ...



SCCS Notes of Guidance for the testing of cosmetic ingredients and

SAFETY EVALUATION OF COSMETIC INGREDIENTS AS APPLIED BY THE SCCS . 3-5.2.2 TTC approach for human health risk assessment of chemical substances and.



Opinion of the Scientific Committee on Consumer Products on 2

8 jui. 2012 The SCCP (now SCCS)/SCHER/SCHENIHR (SCs) were asked to evaluate potential applications of the Threshold of Toxicological Concern (TTC) approach ...



the sccs notes of guidance for the testing of cosmetic ingredients

31 mar. 2021 SAFETY EVALUATION OF COSMETIC INGREDIENTS AS APPLIED BY THE SCCS . ... 3-5.2.2 TTC approach for human health risk assessment of chemical ...



THE SCCS NOTES OF GUIDANCE FOR THE TESTING OF

SAFETY EVALUATION OF COSMETIC INGREDIENTS AS APPLIED BY THE SCCS . TTC approach for human health risk assessment of chemical substances and cosmetic.



The European Commission non-food Scientific Committees

Committees. Scientific Committee on consumer safety - SCCS Threshold of toxicological concern (TTC) ... decision tree and definition of a TTC value.



The Threshold of Toxicological Concern (TTC) is a Pragmatic Risk

Notes of Guidance SCCS/1602/18. [5] https://phytochem.nal.usda.gov/phytochem/search/. [6] Re TA et al (2009). Application of the TTC approach for the safety 



THE SCCS NOTES OF GUIDANCE FOR THE TESTING OF

SAFETY EVALUATION OF COSMETIC INGREDIENTS AS APPLIED BY THE SCCS . TTC approach for human health risk assessment of chemical substances and cosmetic.



THE SCCS NOTES OF GUIDANCE FOR THE TESTING OF

25 avr. 2016 The use of the TTC approach for cosmetics and consumer products has been evaluated by the SCCS/SCHER/SCENHIR (SCCP/1171/08).



Scientific Committee on Consumer Safety (SCCS) Meeting of the

27 fév. 2019 Heli Hollnagel DOW Europe



Scientific Committee on Consumer Safety (SCCS) Meeting of the

14 sept. 2022 It was stressed that safety assessment of the annexed substances should not be limited to the use of TTC alone but in combination with ...



An ASEAN guidance document for evaluating the safety of

Threshold of Toxicological Concern (ttc) A tool for assessing Substances of unknown Toxicity present at low levels in the diet ILSI Europe concise monograph series ILSI Press 2005 6 Refinement of the Dermal Sensitisation Threshold (DST) approach using a larger dataset and incorporating mechanistic chemistry domains

What is the TTC approach?

The TTC approach is an appropriate strategic component for many cosmetic fragrances due to low use concentrations. The TTC approach can be applied to hair dyes with low use concentration and intermittent consumer exposure. The TTC approach is adequate for plant extracts provided an absence of genotoxic activity is demonstrated. 1. Introduction

What does SCCS do?

SCCS The Committee shall provide opinions on questions concerning all types of health and safety risks (notably chemical, biological, mechanical and other physical risks) of

What does sccs/1552 stand for?

Opinion of the Scientific Committee on Consumer Safety on o-aminophenol (A14) SCCS/1552/15 Scientific Committee on Consumer Safety SCCS OPINION ON ?-arbutin

What is a TTC classification?

For a TTC approach, the SCCS (and other SCs) accept in principle the division into Cramer Classes I and III (SCCP/1171/08). When assigning a chemical to the lowest toxicity class (Class I, 1800 µg/person/d for substances with no genotoxicity alert), classification should be carefully considered and justified.