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he sixth edition of Modern Pharmacology With Clinical Applications continues our commitment to enlisting experts in pharmacology to provide a textbook that is up-to-date and comprehensive De-signed to be used during a single semester the book fo-cuses on the clinical application of drugs within a con-

PHARMACOLOGICAL PRINCIPLES

116 PSYCHIATRIC-MENTAL HEALTH NURSE PRACTITIONER REVIEW AND RESOURCE MANUAL 4TH EDITION MEDICATIONS USED TO T REAT MOOD DISORDERS UNIPOLAR AFFECTIVE DISORDERS AND DEPRESSIVE DISORDERS Tricyclics (TCAs) Clomipramine (Anafranil) Amoxapine (Asendin) Amitriptyline (Elavil) Desipramine (Norpramin) Nortriptyline (Pamelor) Doxepin (Sinequan)

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iii Gary C Rosenfeld PhD Professor Department of Integrated Biology and Pharmacology and Graduate School of Biomedical Sciences Assistant Dean for Education Programs University

What is the pharmacological management process?

Pharmacological management process: Make a diagnosis and identify the target symptoms. Consider the phase of illness (such as acute, relapse, recurrence). Assess prior personal and family history of response to certain medications. Assess the client’s motivation for and any misgivings about treatment.

What is psychopharmacology?

Psychopharmacology, one of the most active and developing areas of psychiatric research, is the use of psychotropic medication to treat psychiatric disorders.

What does pharmacokinetics mean?

Pharmacokinetics: Study of what the body does to drugs; includes absorption, distri-bution, metabolism, and excretion Pharmacodynamics: Study of what drugs do to the body; target sites for drug actions include receptors, ion channels, enzymes, and carrier proteins Absorption: Method and rate at which drugs leave the site of administration