https://www.cell.com/cell-reports/pdf/S2211-1247(19)31720-6.pdf
Jun 20 2019 secondary infection with an antigenically distinct influenza virus requires memory B-cell activation. These activated memory B cells were ...
May 15 2013 After the B cells become activated
Oct 28 2016 We show that T-independent stimulation with CpG measures proliferation and differentiation potential of memory B cells. Switched memory B cells ...
Jul 22 2019 revealing an activated memory B cell state associated with ... neighborhood as activated memory B cells
Aug 12 2014 Although the importance of Bcl6 and its expression kinetics in naïve T-cell differentiation have been well elucidated
indicating that CD27 is a memory marker of B cells. The ligation of CD27 yields crucial signals somatic hypermutation B cell activation
Activation of memory B cells by TLR9 can lead to cellular expansion and immunoglobulin production and this may play an important role in memory B cell home
T cell-dependent hu- moral (antibody) immune responses are ini- tiated by activation of nafve and memory B cells in the T cell-rich extrafollicular areas.
13 nov 2014 · B cells are generated in the bone marrow • Takes 1-2 weeks to develop from hematopoietic stem cells to mature B cells
The mature B cells become activated in the T cell zones of P ALS and then migrate into B cell zones to form germinal centers To produce antibodies the
Antibodies are produced only by B lymphocytes • Humoral immune responses are initiated by binding of antigen to membrane bound antibody on B cells
1 sept 2019 · For activation and differentiation into antibody-secreting plasma cells mature B cells in the periphery lymphoid organs require two signals
21 jan 2020 · We profile the molecular and cellular features of the antibody response to influenza vaccination by integrating sin- gle-cell transcriptomics
Here we explain how B cell mem- ory is generated by infection and vaccination what influences its efficacy and its persistence and how char- acterizing these
22 juil 2019 · In subsequent encounters memory B cells are rapidly 36 activated leading to clonal expansion and differentiation to antibody-secreting cells
13 déc 2019 · Antigens encountered on follicular dendritic cells (FDCs) activate B cells through the B cell receptor (BCR) and the antigens are processed and
23 mar 2009 · B Cell Activation Ab Responses to few Ags does not require thymus (TI) Response is mainly IgM with no memory TI-1 Ags Bacterial cell wall
This transcriptional program putatively results from specific interactions (e g OX-40 CD23) during activation [1011] It is believed that when B cells commit