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Antisense oligonucleotides for Alzheimers disease therapy: from the

10 nov. 2021 Abbreviations: AD Alzheimer's disease; Ab



New RNA-Based Breakthroughs in Alzheimers Disease Diagnosis

3 sept. 2021 Keywords: Alzheimer's disease; amyloid hypothesis; dementia; diagnosis; ... Short single-stranded synthetic oligonucleotides can control the.



NucleicAcid-Based Theranostics for Tackling Alzheimers Disease

5 sept. 2017 Key words: nucleic acids; Alzheimer's disease; amyloid beta peptides; tau peptide; chemically modified oligonucleotides; nucleic acid ...



Targeting MicroRNA-485-3p Blocks Alzheimers Disease Progression

Keywords: Alzheimer's disease; ?-amyloid; tau; IL-1?; TNF-?; neuroinflammation; cognitive function; microRNA; miR-485-3p; antisense oligonucleotide.



Rationale for and development of Ionis-MAPTRx the first tau

17 oct. 2017 oligonucleotide drugs can be found at ... In Alzheimer disease tau is not mutated yet neurofibrillary tangles form and tau.



Identification and characterization of a MAPT-targeting locked

the H1 haplotype.910 In Alzheimer's disease (AD) and FTLD-Tau



Towards Personalized Allele-Specific Antisense Oligonucleotide

16 août 2022 Keywords: antisense oligonucleotide; ASO; neurodegenerative diseases ... (PD) Alzheimer's disease (AD) and spinocerebellar ataxia (SCA) are ...



Towards Personalized Allele-Specific Antisense Oligonucleotide

16 août 2022 Keywords: antisense oligonucleotide; ASO; neurodegenerative diseases ... (PD) Alzheimer's disease (AD) and spinocerebellar ataxia (SCA) are ...



Neuromuscular disease: Antisense oligonucleotide shows promise

26 févr. 2016 The antisense oligonucleotide nusinersen is safe and tolerable ... neurotoxic species in Alzheimer disease (AD). Experiments in.



Modulation of blood-brain barrier function by a heteroduplex

Alzheimer's disease and stroke1