Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell
Oct 4 2016 interaction and is driven by self-antigens. These class-switched autoreactive thymic B cells play an important role in. CD4 T cell tolerance ...
B Cell Tolerance to Self-Antigens in Ets1 Requirement for
Interestingly high-affinity soluble self-antigen did cause B cells to adopt many of genes to mice carrying BCR transgenes that allow B cell tolerance.
Thymic B Cells Are Licensed to Present Self Antigens for Central T
Thymic B cells present a licensing-dependent endogenous self-antigen for negative selection Self Antigens for Central T Cell Tolerance Induction.
B-cell tolerance checkpoint violations in systemic lupus erythematosus
antigens. It is also important that the B cells do not respond to self-antigens as this would lead to autoimmune diseases.
B Cell Tolerance in Health and Disease
Feb 19 2014 However
Central B-Cell Tolerance: Where Selection Begins
tral B-cell tolerance in fact
Tâ• or B
Apr 16 2014 In mice
Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T
Sep 17 2019 cific T cells escaping central tolerance acclimate to self-antigen ... (B) iFABP-Ova mice were (+VSV-Ova) or were not.
Autoreactive thymic B cells are efficient antigen-presenting cells of
Oct 15 2013 tolerance in the thymus. This process depends on presentation of self-peptides to developing thymocytes by antigen-presenting cells (APCs).
Self-antigen does not accelerate immature B cell apoptosis but
of self-tolerance and positive selection during B cell develop- Self-Antigen Arrests the Development of Autoreactive B. Cells and Blocks Positive ...
