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B-cell activation by crosslinking of surface IgM or ligation of CD40



A p38 MAPK-MEF2C pathway regulates B-cell proliferation

4 nov. 2008 These data suggest a pathway in which MEF2C acts downstream of BCR signaling via the p38 MAPK cascade to drive B-cell.



B Cell Receptor and CD40 Signaling Are Rewired for Synergistic

30 janv. 2018 show that CD40 and BCR signaling in GC B cells is rewired to control very different pathways and both signals are required for optimal ...



Role of CD27/CD70 pathway of activation in immunity and tolerance

NF-B pathway [10]. The murine CD70 is a homotrimeric type. II transmembrane glycoprotein expressed on activated DCs B cells



Specific hypomethylation programs underpin B cell activation in

15 déc. 2021 an enrichment in B cell activation and differentiation cytokine production



B-Cell Development Activation

https://www.roswellpark.org/sites/default/files/holstein_b_cell_lecture_11-13-14.pdf



The B-cell activation pathway in human systemic lupus

The B-Cell Activation Pathway in Human Systemic Lupus. Erythematosus: Imbalanced in Vitro and IL-2 interleukins 1 and 2; BCGF



The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell

20 juil. 2010 Activation of the B-cell antigen receptor (BCR) signaling pathway contributes to the initiation and maintenance of B-cell malignancies.



EZH2 Inhibition by Tazemetostat Results in Altered Dependency on

cell maturation and a greater dependence on B-cell activation signaling. EZH2 alters how cells respond to this signaling pathway.



Interferon-λ Enhances the Differentiation of Naive B Cells

6 oct. 2020 signaling and boosts B cell differentiation by enhancing mTORC1 activity and cell- ... in human B cells via the JAK-STAT signaling pathway.