18 avr. 2019 B cells and the antibodies they produce have a deeply penetrating influence on human physiology. Here we review current understanding of ...
In this review we summarize some of the B cell anoma- lies in SLE and incorporate evidence from studies in humans and mouse models
27 mars 2022 Here we review human hematopoiesis at each end of the age spectrum ... human fetal B cell development has recently been reviewed [119]
B-cell development takes place in distinct differentiation REVIEWS. Table 1
21 mars 2022 Human Immunodeficiency Virus (HIV) and other chronic inflammatory conditions [25
18 août 2022 In this review we focus on the role of microRNAs in controlling B-1 and B-2 development and in the hemato- logical B-cell malignancies that ...
Acad. Sci. USA. Vol. 93 pp. 10348-10353
4 mars 2022 This review focuses on a relatively unexplored immune ... pool in adult humans (1–3% of total adult B cells in the blood and peritoneal ...
model system they showed that cells that develop in the bursa of Fabricus (equivalent to the bone marrow in mouse and human) are responsible for antibody
28 janv. 2020 Single cell gene expression analysis suggested that pre-leukemic cells resided within a subpopulation of early B-cell precursors with ...
This mini-review provides a brief history of the discovery of B cells as well as describes the characteristics of each B cell lineage and the processes of B cell development maturation and activation Finally we highlight the application of B cell biology in the development of novel therapeutics for the treatment of B cell mediated diseases
regulation of human b cell development Human and rodent pancreatic islets are composed of ?ve hormone-secreting endocrine cell types These include the aforementioned a and b cells plus somatostatin-secreting d cells pancreatic polypeptide (PP) cells and the ghrelin-producing e cells During human and rodent development early
human B-cell memory subset expressing the inhibitory re-ceptor Fc-receptor-like 4 (FCRL4) has been described [25] whichislargelyrestrictedtomucosaltissuesandmesenteric lymphnodes TheFCRL4+ and FCRL4 (classical)memory B-cell subsets differ in the expression of transcription fac-tors cell cycle regulators (cyclins) signaling molecules and