Biopharmaceutics questions and answers pdf

  • What are Class 2 drugs in biopharmaceutical classification system?

    BCS classes

    Class I - high permeability, high solubility.
    Example: metoprolol, paracetamol. Class II - high permeability, low solubility.
    Example: glibenclamide, bicalutamide, ezetimibe, aceclofenac. Class III - low permeability, high solubility.
    Example: cimetidine. Class IV - low permeability, low solubility..

  • What is a Class 1 biopharmaceutical classification?

    By definition, BCS Class I drugs are highly absorbed, and have neither solubility nor permeability limited absorption.
    Therefore they generally represent a low risk group of compounds in terms of the potential for excipients to affect absorption, compared to other BCS classes..

  • Which type of drug has highest bioavailability?

    Therefore, a drug given by the intravenous route will have an absolute bioavailability of 100% (f = 1), whereas drugs given by other routes usually have an absolute bioavailability of less than one..

  • Pro- drugs may be considered for a BCS-based biowaiver when absorbed as the pro-drug.
    A drug substance is classified as highly soluble if the highest single therapeutic dose is completely soluble in 250 ml or less of aqueous media over the pH range of 1.2–6.8 at 37\xb11\xb0C.

What is pharmacology question bank?

Our Pharmacology question bank covers all the questions related to above mentioned topics.
International Medical and Technological University.
It is the science of drugs and their effects on the body which incorporates biomedical science, linking together chemistry, physiology and pathology.
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