The NIH Guidelines defines the risk groups as:- Risk Group 1 (RG1) - Agents that are not associated with disease in healthy adult humans.
- Risk Group 2 (RG2) - Agents that are associated with human disease which is rarely serious and for which preventive or therapeutic interventions are often available.
- Risk Group 1. Low individual; low. community. Any biological agent that is unlikely to cause disease in healthy workers or animals.
- Risk Group 2. moderate individual. risk, low community. risk.
- Risk Group 3. high individual risk, low community risk.
- Risk Group 4. high individual risk, high community risk.
Risk Group classifications are based on an agent's capability to infect and cause disease in a susceptible host, severity of disease, and the availability of preventative measures and effective treatments.
Risk Groups are classifications that describe the relative hazard posed by infectious agents or toxins in the laboratory. The risk group to which an
The NIH Guidelines defines the risk groups as: Risk Group 1 (RG1) - Agents that are not associated with disease in healthy adult humans. This group includes a
The World Health Organization (WHO) defines the risk groups as: WHO Risk Group 1 (no or low individual and community risk) - A microorganism that is unlikely to
Biosafety Level 2 - Laboratory Training Requirements
All personnel must receive training on Biosafety Level 2 (BSL-2) laboratory practices prior to working in a BSL-2 laboratory.
Principal Investigators (PIs) are responsible for adhering to the following:.
1) The PI or supervisor must explain the nature of the risks associated with the agent(s) that are used in the lab, the possible routes of exposure.
Biosafety Levels
In contrast to Risk Groups, Biosafety Levels (BSL) prescribe procedures and levels of containment for the particular microorganism or material (including Research Involving Recombinant or Synthetic Nucleic Acid Molecules).
Similar to Risk Groups, BSL are graded from 1 –.
4) Detailed descriptions of containment practices and biosafety levels can be f.
Do risk group levels always correspond to biosafety levels?
Risk group levels do not always correspond to biosafety levels.
For example, a specific research project’s biological risk assessment for the use of human immunodeficiency virus (HIV), a Risk Group 3 agent, may correctly determine that HIV can be handled under Biosafety Level 2 conditions.
Risk Groups
In many countries, including the United States, biological agents are categorized in Risk Groups (RG) based on their relative risk.
Depending on the country or organization, this classification system might take the following factors into consideration:.
1) Pathogenicity of the organism.
2) Mode of transmission and host range.
3) Availability of effec.
What is a Biosafety Level 2 risk assessment for HIV?
For example, a specific research project’s biological risk assessment for the use of human immunodeficiency virus (HIV), a Risk Group 3 agent, may correctly determine that HIV can be handled under Biosafety Level 2 conditions.
Risk groups are designated from 1 (the lowest risk) to 4 (the highest risk).
Which risk groups are included in EHS biosafety?
EHS Biosafety follows the NIH Guidelines categorization of Risk Groups as follows:
RG1 – Are not associated with disease in healthy adult humans or animals RG2 – Are associated with disease which is rarely serious and for which preventative or therapeutics is often available . Working at Biosafety Level 1
Before beginning work at BSL-1 researchers must….
1) Be listed on an approved IBC Inventory and Activity Registration (IAR) (log-in).
2) Complete either:
Working at Biosafety Level 2
Before beginning work at BSL-2 researchers must….
1) Be listed on an approved IBC Inventory and Activity Registration (IAR) (log-in).
2) Complete Bloodborne Pathogen and Biosafety Training for Research Personnel (log-in).
3) Read and sign the BSL-2 Biosafety Manual.
4) May need to enroll in the Medical Surveillance Programand complete medical clearance.
