How is Porphyromonas gingivalis diagnosed?
PCR allows the specific amplification of target bacterial DNA in samples for which the background caused by other species is high.
Thus, PCR could be applicable for the detection of P. gingivalis from saliva..
Is P. gingivalis pathogenic?
P. gingivalis is a significant pathogen of subgingival biofilm [25,26].
In vivo studies in mice have shown that infection with P. gingivalis causes bone resorption [122]..
Is Porphyromonas gingivalis facultative or obligate?
P. gingivalis, a gram-negative strict anaerobe and successful colonizer of oral tissues, can survive, replicate, and spread in GECs [18], [36].
Since the organism can be cultured in-vitro and is a prominent member of oral biofilms, P. gingivalis is considered a facultative intracellular pathogen..
What is the biochemical test for Porphyromonas?
Biochemical tests are Oxidase and Catalase were done to confirm Porphyromonas gingivalis identification morphologically..
What is the pathogenicity of Porphyromonas gingivalis?
P. gingivalis is most associated with chronic periodontitis [16].
However, it significantly contributes to the pathogenesis of aggressive periodontitis by inducing high levels of proinflammatory cytokines [16,139]..
What is the role of Porphyromonas gingivalis?
gingivalis play important roles in the coaggregation, biofilm formation, and oral microbial dysbiosis.
They can either directly act on other bacteria or induce an optimal environment.
One example of direct interaction is that P. gingivalis binds to GAPDH and surface proteins on the surface of S..
What is the taxonomy of Porphyromonas gingivalis?
Porphyromonas gingivalis belongs to the phylum Bacteroidota and is a nonmotile, Gram-negative, rod-shaped, anaerobic, pathogenic bacterium..
Where is Porphyromonas gingivalis found?
The major habitat of P. gingivalis is the subgingival sulcus of the human oral cavity..
Why is Porphyromonas gingivalis often difficult to eliminate?
These so-called biofilms play an important role in the development and pathogenesis of many infections, as they are difficult to eradicate due to their resistance to antimicrobials and host defense mechanisms.
This review focusses on the biofilm-forming periodontal bacterium Porphyromonas gingivalis..
- P. gingivalis, a gram-negative strict anaerobe and successful colonizer of oral tissues, can survive, replicate, and spread in GECs [18], [36].
Since the organism can be cultured in-vitro and is a prominent member of oral biofilms, P. gingivalis is considered a facultative intracellular pathogen. - PCR allows the specific amplification of target bacterial DNA in samples for which the background caused by other species is high.
Thus, PCR could be applicable for the detection of P. gingivalis from saliva. - Porphyromonas gingivalis belongs to the phylum Bacteroidota and is a nonmotile, Gram-negative, rod-shaped, anaerobic, pathogenic bacterium.
- Porphyromonas gingivalis is a Gram-negative anaerobic bacterium and is considered to be a major pathogen associated with periodontitis.
Since this bacterium is known to be a very poor carbohydrate utilizer and cannot take up free amino acids, it only utilizes short oligopeptides as carbon and energy sources.
