Computer aided drug design ppt

How to do computer-aided drug design?
CADD approach can be utilized in 4 phases: (1) screen small molecule library against the target using virtual screening (VS) protocol to identify hits/leads, (2) investigate specificity of the selected hits from VS using molecular docking in the active site of other known targets, (3) predicting ADMET properties of the .
What are the steps in SBDD?
Drug design begins with an identification of a biological target (a biomacromolecule involved in the disease).
Then, a ligand interacting with this macromolecule, known as a hit molecule, has to be discovered..
What is Lbdd in bioinformatics?
Ligand-based drug discovery (LBDD) refers to drug discovery efforts in absence of any target structures and in presence of chemical structures known to modulate the target..
What is the application of CAD in pharmacy?
The primary objective of CADD is to screen, optimize and evaluate the activity of the compound against the target.
It forms the multi-disciplinary approach for both academic and major pharmaceutical companies for better efficacy with no/fewer side effects..

Mar 10, 20173. Drug Design SLIDE 3 is the inventive process of finding new medications based on the knowledge of a biological target. It involves the

How to do computer-aided drug design?