Crystallography cro

  • How is a protein Crystallised?

    Vapor diffusion is the most commonly employed method of protein crystallization.
    In this method, droplets containing purified protein, buffer, and precipitant are allowed to equilibrate with a larger reservoir containing similar buffers and precipitants in higher concentrations..

  • In vapor diffusion, a drop containing a mixture of precipitant and protein solutions is sealed in a chamber with pure precipitant.
    Water vapor then diffuses out of the drop until the osmolarity of the drop and the precipitant are equal (Figure .
    1. A)
Use X-Ray crystallography to generate protein-ligand complexes that provide invaluable insights to your drug discovery teams.

What is serial crystallography?

Serial crystallography experiments in standard and lipidic cubic phase media An interactive online software suite that tracks experiments and results, and makes them available to scientists in real-time through intuitive interfaces

Remote-controlled web-based workflows, from pure protein to refined structures

Why should you use a crystallographer for a drug design project?

The resulting structures, combined with the significant industrial design experience of our crystallographers and integrated with results from advanced biophysical assays, allow us to detail protein-ligand interactions at a structural, kinetic and thermodynamic level and provide insight to drug design projects

Why should you use X-ray crystallography?

Use X-Ray crystallography to generate protein-ligand complexes that provide invaluable insights to your drug discovery teams

Benefit from the experience of our in-house crystallographers to gain structural, kinetic and thermodynamic data from your structures and integrated biophysical assay results


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