Protein crystallography history

What is the historical background of crystallography?
The discovery of crystallography
The story of crystallography dates back to 1912.
German physicist Max von Laue and colleagues were experimenting with mysterious X-rays – scientists were still not entirely sure if they were electromagnetic waves like light and radio waves – and various crystals..
What is the history of protein crystallization?
Protein crystallization was discovered by chance about 150 years ago and was developed in the late 19th century as a powerful purification tool and as a demonstration of chemical purity..
Who invented protein crystallography?
This is the first X‐ray diffraction pattern of a protein crystal.
In 1958, the structure of myoglobin (a red protein containing heme), determined by X-ray crystallography, was first reported by John Kendrew.
Kendrew shared the 1962 Nobel Prize in Chemistry with Max Perutz for this discovery..
However, it was Perutz who pioneered the methodology of protein crystallography, especially the method of isomorphous replacement (see below) for the solution of the phase problem [31].

Apr 3, 2014The practical use of MR was pioneered by Michael Rossmann and David Blow (1931–2004) [77-79]. This approach has also evolved significantly and, Early days of crystallographyCrystallization of Dorothy Hodgkin, who put bio

Abstract. Protein crystallization has been known since 1840 and can prove to be straightforward but, in most cases, it constitutes a real bottleneck. This stimulated the birth of the biocrystallogenesis field with both 'practical' and 'basic' science aims.

Before the first protein crystal was solved (from Selected Reviews below):. 1895: W. C. Roentgen discovers X rays (Bragg, p. 1).

When was protein crystallization discovered?

Protein crystallization was discovered by chance about 150 years ago and was developed in the late 19th century as a powerful purification tool and as a demonstration of chemical purity

Who invented isomorphous replacement in protein crystallography?

The pioneering work of Max F

Perutz (1914–2002, Fig

1) in the application of isomorphous replacement was the start of great successes in protein crystallography

The essence of the technique is succinctly, but clearly described in the Perutz quotes below

Class of peptides which help cells survive freezing conditions

Antifreeze proteins (AFPs) or ice structuring proteins refer to a class of polypeptides produced by certain animals, plants, fungi and bacteria that permit their survival in temperatures below the freezing point of water.
AFPs bind to small ice crystals to inhibit the growth and recrystallization of ice that would otherwise be fatal.
There is also increasing evidence that AFPs interact with mammalian cell membranes to protect them from cold damage.
This work suggests the involvement of AFPs in cold acclimatization.

Protein crystallography history

What is the historical background of crystallography?

What is the history of protein crystallization?

Who invented protein crystallography?

When was protein crystallization discovered?

Who invented isomorphous replacement in protein crystallography?