Cytology false negatives

  • What are false negative results?

    A test result that incorrectly indicates that the condition being tested for is not present when, in fact, the condition is actually present.
    For example, a false-negative HIV test indicates that a person does not have HIV when the person actually does have HIV..

  • What are the causes of false negatives of Pap smear?

    Factors that can cause a false-negative result include:

    An inadequate collection of cells.A small number of abnormal cells.Blood or inflammatory cells obscuring the abnormal cells..

  • What causes a false negative HPV test?

    This can happen because: sometimes abnormal cells do not look much different to normal cells. there may be very few abnormal cells in the sample..

  • False negative smears were identified in 27.1% of women with CC (ADC 52.6% vs.
    SCC 16.2%, p\x26lt;0.05).
A smear was scored as being false negative under two circumstances: if, on the visit on which the negative smear was obtained, dys- plasia or carcinoma in situ 
In order to assess the false nega- tive rate in cytology of the uterine cervix, the patients with positive smears must first be eliminated from a population and 

Does fine needle aspiration cytology cause false negative diagnoses?

Layfield LJ, Dodd LG.
Cytologically low grade malignancies:

  1. An important interpretative pitfall responsible for false negative diagnoses in fine-needle aspiration of the breast

Diagn Cytopathol. 1996;15:250–9. [ PubMed] [ Google Scholar] 99.
Bhatia A.
Fine needle aspiration cytology in the diagnosis of mass lesions of the salivary gland.
,

What causes false negative cytology reports?

Factors contributing to false-negative and potential false-negative cytology reports in SurePath™ liquid-based cervical cytologyMicrobiopsies/HCGs were the commonest reason for false negatives.
They were usually present in sufficient numbers to be detected but interpretation could be problematic.


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