Neutrophils in the PAP smear, which are found in infections (bacterial, fungal or viral) – are associated with and are phagocytosed by Trichomonas [2] and Chlamydia [3]..
Inflammation of the cervix is common, and some neutrophils are present in most cervical smears.
When neutrophils are abundant, the squamous cell component may be obscured, resulting in satisfactory but limited smears, or unsatisfactory smears.
Inflammatory cells may be associated with a specific infectious agent eg..
Neutrophils in the PAP smear are a nonspecific finding, particularly if they are low in numbers or if they are seen in the premenstrual and the menstrual phases.
The neutrophils which are adherent to the squamous cells are called “cannon balls” or “pus balls”, which are common in the Chlamydia infection.Aug 1, 2013.
Spindle Cells:
Indicators of neoplasia include absence of a reactive stimulus, such as inflammation or hemorrhage, and a higher cell population with more numerous and larger clumps of cells.
Greater variation in cell morphology indicates more aggressive behavior..
Neutrophils in the PAP smear are a nonspecific finding, particularly if they are low in numbers or if they are seen in the premenstrual and the menstrual phases.
The neutrophils which are adherent to the squamous cells are called “cannon balls” or “pus balls”, which are common in the Chlamydia infection.Aug 1, 2013.
Recent reviews have provided a comprehensive analysis of the function of neutrophils in cancer and tumour resistance, as well as their clinical relevance to patients with cancer 14, 15
Here we discuss our current knowledge of the relationship between neutrophils and cancer, with emphasis on the context-dependent activities of these cells
The release of neutrophils is tightly controlled since only 1 or 2% of all neutrophils in the body are found in the blood under normal homeostatic conditions
Mature neutrophils are kept in the bone marrow through the action of two chemokine receptors, CXCR2 and CXCR4
They circulate in the blood for 6-10 hours, and then enter the tissues
They are motile, and phagocytic and will destroy damaged tissue and bacteria
They self destruct after one burst of activity
They are important in inflammatory reactions
