Dental pulp stem cells anatomy

  • How do you extract stem cells from dental pulp?

    In the cell processing center, the pulp is retrieved either by using sterile barbed broach or by cutting the tooth using diamond disc along with coolant to avoid damage to the pulp.
    The isolated pulp is then trypsinized and cultured to yield colonies of stem cells..

  • What is the anatomy of the pulp of the tooth?

    The pulp is a mass of connective tissue that resides within the center of the tooth, directly beneath the layer of dentin.
    Referred to as part of the “dentin-pulp” complex, and also known as the endodontium, these two tissues are closely interrelated and dependent on each other's development and survival..

  • What is the cell of the dental pulp?

    Cells found in the dental pulp include fibroblasts (the principal cell), odontoblasts, defence cells like histiocytes, macrophage, granulocytes, mast cells and plasma cells.
    The nerve plexus of Raschkow is located central to the cell-free zone..

  • What type of stem cells are in dental pulp?

    Dental pulp progenitor cells are derived from mesodermal tissues and have been originally described by Gronthos et al. 11 They are closely related to mesenchymal (stromal) stem cells (MSC) that are present in the stromal compartment of different tissues including bone marrow..

  • Where do dental pulp stem cells come from?

    Dental pulp progenitor cells are derived from mesodermal tissues and have been originally described by Gronthos et al. 11 They are closely related to mesenchymal (stromal) stem cells (MSC) that are present in the stromal compartment of different tissues including bone marrow..

  • Dental follicle stem cells (DFSCs), which are the stem cells present in the dental follicle tissue of the tooth germ and are derived from the neural crest, are direct precursor cells of periodontal tissues and can form the periodontal ligament, cementum, and alveolar bone proper in the late stage of tooth development.
  • Tooth pulp elaborates and repairs the calcified tissues in which it is enclosed; it responds to irritation by producing patterns of neural activity which give rise to painful sensation; and it maintains the vitality of its cellular constituents by providing oxygen and nutrients sufficient for their metabolic
Dental pulp progenitor cells are derived from mesodermal tissues and have been originally described by Gronthos et al. 11 They are closely related to mesenchymal (stromal) stem cells (MSC) that are present in the stromal compartment of different tissues including bone marrow.
Dental pulp progenitor cells are derived from mesodermal tissues and have been originally described by Gronthos et al.11 They are closely related to mesenchymal 
Dental pulp stem cells (DPSCs) are a unique population of cells embedded within the pulp cavity of the impacted third molars. DPSCs were initially isolated and characterized by Gronthos et al. (2000).

What are dental pulp stem cells?

Dental pulp stem cells have been used in an increasing number of studies in dental tissue engineering

Those cells show mesenchymal (stromal) stem cell-like properties including self-renewal and multilineage differentiation potentials, aside from their relative accessibility and pleasant handling properties

What is dental pulp?

Dental pulp is anunmineralized connective tissue that is composed of stem cells as well as fibroblastic cells, capillary blood vessels, peripheral nerves, lymphatic elements, and extracellular matrices and odontoblasts on the periphery of pulp tissue

Where do stem cells come from in a root canal?

Because stem cells (DPSCs) are present in the dental pulp, the source of the cells depends on whether the vital pulp is preserved in the root canal

Pulpotomy is a dental procedure that removes the pulp of a tooth in the crown and leaves the pulp in the root canal as intact vital pulp


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