Dental surgery and prolia

Can I have a dental implant if I take Prolia?
If you are taking medications for osteoporosis such as alendronate (Forsamax), risedronate (Actonel), ibandronate (Boniva), or denosumab (Prolia), then your implant dentist may recommend a two month drug holiday before your implant procedure..
Can you get dental implants if you are on Prolia?
If you are taking medications for osteoporosis such as alendronate (Forsamax), risedronate (Actonel), ibandronate (Boniva), or denosumab (Prolia), then your implant dentist may recommend a two month drug holiday before your implant procedure..
Can you have dental surgery while on Prolia?
Prolia is different from other Antiresorptives.
Prolia does not accumulate in bone. 5 to 6 months after your last dose, Prolia has lost its effect of slowing bone turnover.
Therefore, it is safe to proceed with surgery on bone (including dental surgery) 6 months after your last dose..
Does Prolia cause osteonecrosis of the jaw?
Bisphosphonates, like alendronate (Fosamax), risedronate (Actonel and Atelvia), ibandronate (Boniva), zoledronic acid (Reclast) and denosumab (Prolia), may raise ONJ risk.
This may be due to loss of bone's ability to repair itself, a drop in blood vessel formation or infection..
How common is osteonecrosis of the jaw with Prolia?
A total of 3,068 adults in the cohort received bisphosphonates, denosumab (Prolia, Amgen) or both sequentially.
There were 17 diagnoses of osteonecrosis of the jaw, with 12 coming in people receiving denosumab and five in patients on bisphosphonate therapy..
What is the risk of developing osteonecrosis following dental extractions for patients on denosumab for osteoporosis?
The risk of ONJ in patients on denosumab for osteoporosis is a magnitude greater than for patients on the oral bisphosphonates 2.3% v 0 - 0.3%, which is 7.7 times more likely..
Because Bisphosphonate drugs last in the bone for a considerable amount of time even after stopping the medication, it is typically not recommended for the patient to stop taking their bisphosphonate medication prior to tooth extraction.
Dental Care for Patients Prescribed Bisphosphonates
Preventive care and regular dental cleanings are very important.
Routine dental treatment, including fillings, crowns and root canal therapy can be safely undertaken, and is strongly encouraged to prevent future dental problems.
The risk of ONJ in patients on denosumab for osteoporosis is a magnitude greater than for patients on the oral bisphosphonates 2.3% v 0 - 0.3%, which is 7.7 times more likely.

Prolia has a side effect in patients who have to have tooth extractions performed. The trauma of the extraction on the bone surrounding the tooth may lead to a condition where the bone dies off, and following the extraction fragments of dead bone are lost from the extraction site.

The extractions for Prolia patients should therefore take place near the end of the 6 months after Prolia was last administered and ideally 2-3 weeks before the 6 month point so that adequate healing may take place before the next Prolia is given.

Can Oral surgeons perform implant surgery?

Who can perform dental implants.
Oral surgeons.
Oral surgeons are the best-qualified for the surgical aspect of implant treatment.
Oral surgeons have a sound knowledge of the various anatomic landmarks in your jaw bone.
Hence, they have the most expertise in the matter of surgical placement of the implants.

Dental and Jaw-Related Side Effects

Although rare, it’s possible to have dental and jaw-related side effects from using Prolia.
Symptoms of dental and jaw-related side effects can include: 1. loosening of the teeth 2. jaw painor numbness 3. mouth infections One potential complication is jaw necrosis (death of jawbone tissue).
This may cause teeth to become loose and need to be remove.

Does Prolia cause dental problems?

Prolia can cause dental side effects, including:

jaw necrosis (death of jawbone tissue)

Having dental work, such as:surgery or a tooth extraction, can increase your risk for this side effect.
Before beginning treatment with Prolia, be sure to tell your doctor about any dental work you’ve scheduled.
Low blood calcium level.

Is Prolia a safe treatment option for osteoporosis?

The Prolia brand of denosumab is used to treat osteoporosis in postmenopausal women who have high risk of bone fracture.
Prolia is used to increase bone mass in men with osteoporosis with a high risk of bone fracture, and in women and men with a high risk of bone fracture caused by receiving treatments for certain types of cancer.

Joint Pain

Pain, including joint pain, is a possible side effect of Prolia.
Joint pain was mild in studies.
But after these studies were done, some people have reported severe joint pain while using Prolia.

Risk of Bone Fractures After Skipping Or Stopping Treatment

Skipping a dose of Prolia or stopping use of the drug increases the risk of bone fractures.
This includes an increased risk of multiple bone fractures in the spine.
When stopping Prolia, bone turnover increases to above-usual values 9 months after the last dose. “Bone turnover” refers to how quickly your bones replace old bone tissue with new bone .

Unusual Fractures in The Thigh Bone

While rare, Prolia has caused unusual fractures in the thigh bone.
Symptoms of a thigh bone fracture are new or unusual feelings of pain in the hip, thigh, or groin.

Dental surgery and prolia

Can I have a dental implant if I take Prolia?

Can you get dental implants if you are on Prolia?

Can you have dental surgery while on Prolia?

Does Prolia cause osteonecrosis of the jaw?

How common is osteonecrosis of the jaw with Prolia?

What is the risk of developing osteonecrosis following dental extractions for patients on denosumab for osteoporosis?