Dermatology antimicrobial resistance

Can topical antibiotics cause antibiotic resistance?
Excessive use of topical antibiotics is known to be a key driver of AMR, and is directly responsible for increasing antibacterial resistance in S. aureus..
How do you prevent antibiotic resistance from acne?
Both the European and AAD guidelines recommend using topical benzoyl peroxide or a retinoid as first-line therapy for acne.
The guidelines also converge on the recommendation to avoid antibiotic monotherapy, whether oral or topical..
How does antimicrobial resistance occur?
About Antimicrobial Resistance
Antimicrobial resistance happens when germs like bacteria and fungi develop the ability to defeat the drugs designed to kill them.
That means the germs are not killed and continue to grow.
Resistant infections can be difficult, and sometimes impossible, to treat..
What are the 4 types of antimicrobial resistance?
Antimicrobial resistance mechanisms fall into four main categories: (1) limiting uptake of a drug; (2) modifying a drug target; (3) inactivating a drug; (4) active drug efflux..
What are the methods of antimicrobial resistance?
The three fundamental mechanisms of antimicrobial resistance are (1) enzymatic degradation of antibacterial drugs, (2) alteration of bacterial proteins that are antimicrobial targets, and (3) changes in membrane permeability to antibiotics..
What is the antimicrobial resistance?
Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi and parasites change over time and no longer respond to medicines making infections harder to treat and increasing the risk of disease spread, severe illness and death..
What is the most common antibiotic for dermatologists?
Tetracyclines are the most common antibiotics prescribed by dermatologists, often for prolonged durations to treat acne vulgaris and rosacea..
Benzoyl peroxide has the following properties: Antiseptic: it reduces the number of skin surface bacteria (but it does not cause bacterial resistance and in fact can reduce bacterial resistance if this has arisen from antibiotic therapy).
It also reduces the number of yeasts on the skin surface.
Excessive use of topical antibiotics is known to be a key driver of AMR, and is directly responsible for increasing antibacterial resistance in S. aureus.
Methicillin-resistant Staphylococcus aureus (MRSA) infection is caused by a type of staph bacteria that's become resistant to many of the antibiotics used to treat ordinary staph infections.

Sep 20, 2021Antibiotics are the mainstay of therapy for common dermatoses, including acne and rosacea, as well as for skin and soft tissue infections.

Antimicrobial resistance leads to clinically significant consequences, including antibiotic treatment failures. In acne patients, the presence of antibiotic-resistant Cutibacterium acnes on skin may be associated with suboptimal patient outcomes from inadequate responses to both topical and oral antibiotics.

Research efforts are now aimed at understanding how antibiotic prescribing in dermatology leads to the development of antimicrobial resistance. Evidence from human microbiome studies suggests that antibiotic regimens typically used in dermatology can trigger expansion of antibiotic-resistant skin bacteria.

Are topical treatments a risk factor for antibiotic resistance?

Adult patients with AV and parents of younger patients with AV have a general understanding of the risks associated with antibiotic resistance and many of the potential causes of antibiotic resistance; however, they underestimate the role of topical treatments in the development of antibiotic resistance.

Is antibiotic resistance a threat to public health?

Background:

Antibiotic resistance presents a threat to public health

In dermatology, antibiotics are used extensively for the treatment of acne, sometimes for extended periods.
Thus, awareness of antibiotic resistance among dermatology patients is relevant in clinical practice.

What are antimicrobials and antimicrobial resistance?

Antimicrobials – including:

antibiotics
antivirals
anti-fungals and anti-parasitics – are medicines used to prevent and treat infections in humans
animals and plants

Antimicrobial resistance (AMR) occurs when bacteria, viruses, fungi, and parasites change over time and no longer respond to medicines hence making infections harder to treat.

What are the drivers of antibiotic resistance?

One major driver of resistance is the overuse and misuse of antibiotics in human healthcare.
Globally, antimicrobial consumption is accelerating worldwide, particularly in LMICs, as the drugs become more accessible and affordable.

Method of assessing antibiotics

The antimicrobial spectrum of an antibiotic means the range of microorganisms it can kill or inhibit.
Antibiotics can be divided into broad-spectrum antibiotics, extended-spectrum antibiotics and narrow-spectrum antibiotics based on their spectrum of activity.
Detailedly, broad-spectrum antibiotics can kill or inhibit a wide range of microorganisms; extended-spectrum antibiotic can kill or inhibit Gram positive bacteria and some Gram negative bacteria; narrow-spectrum antibiotic can only kill or inhibit limited species of bacteria.

Dermatology antimicrobial resistance

Can topical antibiotics cause antibiotic resistance?

How do you prevent antibiotic resistance from acne?

How does antimicrobial resistance occur?

What are the 4 types of antimicrobial resistance?

What are the methods of antimicrobial resistance?

What is the antimicrobial resistance?

What is the most common antibiotic for dermatologists?

Are topical treatments a risk factor for antibiotic resistance?

Is antibiotic resistance a threat to public health?

What are antimicrobials and antimicrobial resistance?

What are the drivers of antibiotic resistance?