Basic Local Alignment Search Tool (BLAST)
The program compares nucleotide or protein sequences and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.
BLAST identifies homologous sequences using a heuristic method which initially finds short matches between two sequences; thus, the method does not take the entire sequence space into account. After initial match, BLAST attempts to start local alignments from these initial matches.
BLAST stands for Basic Local Alignment Search Tool.
It is a widely used bioinformatics program that was first introduced by Stephen Altschul et al. in 1990 and has since become one of the most popular tools for sequence similarity search. Basic Local Alignment Search Tool (BLAST). Image Source: NCBI.
In bioinformatics, BLAST (basic local alignment search tool) is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences.
In bioinformatics, BLAST is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins or BackgroundAlgorithmProgramAlternatives to BLAST
Several key features of BLAST make it a widely used tool in bioinformatics. Some of these are: BLAST is fast and efficient, making it possible to handle large databases of sequences. It is a flexible and versatile tool as it can be used to search for similarities in both nucleotide and protein sequences.
The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to BlastNucleotide BLASTStandard Protein BLASTPrimer-BLAST
The Bioinformatic Harvester was a bioinformatic meta search engine created by the European Molecular Biology Laboratory and subsequently hosted and further developed by KIT Karlsruhe Institute of Technology for genes and protein-associated information.
Harvester currently works for human, mouse, rat, zebrafish, drosophila and arabidopsis thaliana based information.
Harvester cross-links >50 popular bioinformatic resources and allows cross searches.
Harvester serves tens of thousands of pages every day to scientists and physicians.
Since 2014 the service is down.
The Bioinformatic Harvester was a bioinformatic meta search engine created by the European Molecular Biology Laboratory and subsequently hosted and further developed by KIT Karlsruhe Institute of Technology for genes and protein-associated information.
Harvester currently works for human, mouse, rat, zebrafish, drosophila and arabidopsis thaliana based information.
Harvester cross-links >50 popular bioinformatic resources and allows cross searches.
Harvester serves tens of thousands of pages every day to scientists and physicians.
Since 2014 the service is down.