Shining light on location-biased cAMP signaling
paradigm of GPCR signaling via cAMP postulates that ligand bPAC bacteria-derived photoactivable adenylyl cyclase; GPCRs
Microtubules and Actin Microfilaments Regulate Lipid Raft/Caveolae
Raft/Caveolae Localization of Adenylyl Cyclase. Signaling Components* lipid rafts/caveolae thereby regulating the distribution of GPCR.
Evidence for functional pre-coupled complexes of receptor
G protein-coupled receptors (GPCRs) G proteins and adenylyl cyclase (AC) comprise one GPCR heterotetramers that fulfill this scheme
cAMP Signaling Compartmentation: Adenylyl Cyclases as Anchors
07/12/2017 Downstream signalling from Family B GPCR's depend on co-localization to domains with specific ACs since adenylate cyclase-activating.
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cAMP Signaling Compartmentation: Adenylyl Cyclases as Anchors
The classic model of G protein-coupled receptor (GPCR) signaling where receptors
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G protein-regulated endocytic trafficking of adenylyl cyclase type 9
09/06/2020 The beta-2 adrenergic receptor (b2AR) provides a clear example and is generally considered a model for the GPCR family more broadly (Lefkowitz
Physical interaction between neurofibromin and serotonin 5-HT
25/10/2016 Active G protein-coupled receptor (GPCR) conformations not only ... volved in adenylyl cyclase activation by various GPCRs (12 16).
Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat
16/11/2021 [6]. In addition GPCRs and AC3 are colocal- ized in neuronal cilia to mediate cAMP signaling in response to GPCR activation. In a previous ...
Priming GPCR signaling through the synergistic effect of two G
04/04/2017 between GPCR and G proteins show counterintuitive downstream responses. For instance increased adenylate cyclase activity of a.
Members of the KCTD family are major regulators of cAMP signaling
21/12/2021 by adenylyl cyclases (AC) is controlled by G protein–coupled recep- ... chose to investigate KCTD proteins with ties to GPCR signal-.
- adenylyl cyclase gpcr pathway
- adenylate cyclase gpcr