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PDF FLOXAPEN(R) SYRUP

What is FLOXAPEN used for? FLOXAPEN contains flucloxacillin as the active ingredient FLOXAPEN belongs to a group of medicines called penicillins FLOXAPEN is used to treat infections caused by bacteria These infections may affect the chest (pneumonia) the bones (osteomyelitis) or the skin and fleshy tissues FLOXAPEN can also

PDF Package leaflet: Information for the user Floxapen 1000 mg

1 What Floxapen is and what it is used for Floxapen is an antibiotic belonging to a class of antibiotics called beta-lactamase resistant penicillins The active substance is flucloxacillin Flucloxacillin works by killing bacteria that cause infection It only works with specific strains of bacteria Floxapen is used to treat infections such as:

PDF PACKAGE LEAFLET: INFORMATION FOR THE USER

Floxapen is an antibiotic used to treat infections by killing the bacteria that cause them It belongs to a group of antibiotics called “penicillins” Floxapen is used to treat a wide range of infections caused by bacteria including the following: chest infections throat or nose infections ear infections skin and soft tissue infections

  • What is floxapen used for?

    Floxapen is an antibiotic used to treat infections by killing the bacteria that can cause them. It belongs to a group of antibiotics called “penicillins”. chest infections. throat or nose infections. ear infections. skin and soft tissue infections. meningitis. digestive system infections.

  • What are the ingredients in floxapen?

    Each vial contains either 250 mg or 500 mg flucloxacillin as flucloxacillin sodium. There are no other ingredients. Floxapen powder for solution for injection or infusion is a fine white powder. Floxapen is supplied in packs of 10 vials in a carton with a package leaflet. This leaflet was last revised in June 2023.

  • Does floxapen syrup contain sucrose?

    Contains sucrose. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrose-isomaltase insufficiency should not take this medicine. Contains 2.9 g of sucrose per 5 ml dose of Floxapen Syrup 125 mg and contains 2.8 g of sucrose per 5 ml dose of Floxapen Syrup 250 mg.

  • Does floxapen syrup have a teratogenic effect?

    FLOXAPEN Syrup and Syrup Forte contain sodium benzoate. Animal studies with FLOXAPEN have shown no teratogenic effects. The product has been in clinical use since 1970 and the limited number of reported cases in human pregnancy have shown no evidence of untoward effect.

MICROBIOLOGY

FLOXAPEN is a narrow spectrum antibiotic with considerable activity against the following common Gram-positive organisms: Penicillinase producing Staphylococcus aureus Penicillin sensitive Staphylococcus aureus β-haemolytic streptococci (Streptococcus pyogenes) Streptococcus pneumoniae (Diplococcus pneumoniae) It is not active against Streptococcus

PHARMACOLOGY

Blood level studies in fasting subjects show that FLOXAPEN is well absorbed following oral administration with peak levels being achieved within one hour. The presence of food in the gastrointestinal tract delays the absorption of FLOXAPEN resulting in lower peak serum levels. The major route of excretion is renal (by both glomerular filtration an

INDICATIONS

For the treatment of confirmed or suspected staphylococcal and other Gram-positive coccal infections. Indications include pneumonia, osteomyelitis, skin and soft tissue and wound infections, infected burns, cellulitis. apps.medicines.org.au

CONTRAINDICATIONS

FLOXAPEN should not be given to patients with a history of hypersensitivity to beta-lactam antibiotics (eg penicillins, cephalosporins). FLOXAPEN should not be used in the eye, either conjunctivally or locally. Patients with a previous history of flucloxacillin-associated jaundice/hepatic dysfunction. WARNINGS WARNING LIVER TOXICITY: FLUCLOXACILL

FOR

SERIOUS AND OCCASIONALLY FATAL HYPERSENSITIVITY REACTIONS (ANAPHYLAXIS) HAVE BEEN REPORTED IN PATIENTS RECEIVING BETA-LACTAM ANTIBIOTICS. ANAPHYLAXIS HAS OCCURRED IN PATIENTS ON ORAL THERAPY. CROSS-SENSITIVITY BETWEEN PENICILLINS AND CEPHALOSPORINS IS WELL DOCUMENTED. BEFORE COMMENCING THERAPY WITH ANY PENICILLIN, CAREFUL ENQUIRY SHOULD BE MADE CO

PRECAUTIONS

Hepatitis, predominantly of a cholestatic type, has been reported (see Adverse Reactions). Reports have been more frequent with increasing age or following prolonged treatment (more than 14 days). Jaundice may first appear several weeks after therapy; in several cases the course of the reaction has been protracted and lasted for several months. R

Use in Lactation

Flucloxacillin is excreted in breast milk in trace amounts. An alternative feeding method is recommended to avoid any possible sensitisation of the newborn. apps.medicines.org.au

INTERACTIONS

Probenecid decreases the renal tubular secretion of flucloxacillin. Concurrent use with FLOXAPEN may result in increased and prolonged blood levels of flucloxacillin. Loss of activity or physical incompatibility in solution with numerous other drugs has been reported apps.medicines.org.au

Dosage In Patients With Impaired Liver Function

Adjustment of dosage may not be necessary as flucloxacillin is not metabolised in the liver to any appreciable extent. However, during prolonged treatment it is advisable to check periodically for hepatic dysfunction (see precautions). apps.medicines.org.au

OVERDOSAGE

Gastrointestinal effects such as nausea, vomiting and diarrhoea may be evident and should be treated symptomatically. FLOXAPEN is not removed from the circulation by haemodialysis. apps.medicines.org.au

  • Comment prendre le Floxapen ?

    FLOXAPEN peut être administré par injection intraveineuse ou intramusculaire et par perfusion. Votre médecin décidera de la posologie et de la durée du traitement. Celles-ci dépendront de la sévérité et du type d'infection dont vous souffrez.
  • Pourquoi prendre Floxapen ?

    Médicament pour le traitement des infections causées par des bactéries.
  • Comment prendre la Flucloxacilline ?

    La dose quotidienne usuelle est de 25 à 50 mg de flucloxacilline par kg de poids corporel et par jour, répartis en trois ou quatre doses égales, par injection intraveineuse ou intramusculaire. En cas d'infections graves, vous pourrez recevoir jusqu'à 100 mg/kg par jour en trois ou quatre doses.
  • Prescrite pour plusieurs raisons, la ciprofloxacine peut être utilisée pour protéger les gens qui ont côtoyé une personne atteinte d'une méningite, d'une infection bactérienne de la membrane cérébrale ou d'une infection bactérienne du sang.
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What is floxapen syrup?

  • 1 What Floxapen Syrup is and what it is used for Floxapen is an antibiotic used to treat infections by killing the bacteria that can cause them.
    . It belongs to a group of antibiotics called “penicillins”.

How much sodium is in floxapen?

  • Floxapen Syrup contains Sodium Each 5 ml of syrup contains 10.3 mg of sodium.
    . This should be included in the daily allowance of patients on a sodium restricted diet.
    . Floxapen Syrup contains Sucrose Contains sucrose.

How do I add floxapen?

  • Floxapen may be added to most intravenous fluids (e.g.
    . Water for Injections, Sodium Chloride 0.9%, Glucose 5%, Sodium Chloride 0.18% with Glucose 4%).
    . Intramuscular:Add 1.5 ml water for injections to 250 mg vial contents or 2 ml Water for Injections to 500 mg vial contents.

Is floxapen a registered trademark?

  • Floxapen is a registered trademark of the Actavis Group PTC ehf of Companies.










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Floxapen Syrup 125 mg/5 ml Powder for Oral Suspension · 5 How

Floxapen Syrup 125 mg/5 ml Powder for Oral Suspension · 5 How

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RÉSUMÉ DES CARACTÉRISTIQUES DU PRODUIT Les gélules contiennent

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RÉSUMÉ DES CARACTÉRISTIQUES DU PRODUIT Les gélules contiennent

Floxapen Syrup 125 mg/5 ml Powder for Oral Suspension · 5 How

Floxapen Syrup 125 mg/5 ml Powder for Oral Suspension · 5 How

RÉSUMÉ DES CARACTÉRISTIQUES DU PRODUIT Les gélules contiennent

RÉSUMÉ DES CARACTÉRISTIQUES DU PRODUIT Les gélules contiennent

Flucloxacilline - Service Médical en ligne

RÉSUMÉ DES CARACTÉRISTIQUES DU PRODUIT Les gélules contiennent

RÉSUMÉ DES CARACTÉRISTIQUES DU PRODUIT Les gélules contiennent

Floxapen Syrup 125 mg/5 ml Powder for Oral Suspension · 5 How

Floxapen Syrup 125 mg/5 ml Powder for Oral Suspension · 5 How

RÉSUMÉ DES CARACTÉRISTIQUES DU PRODUIT Les gélules contiennent

RÉSUMÉ DES CARACTÉRISTIQUES DU PRODUIT Les gélules contiennent

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