European Conference on Infections in Leukemia Juan-Les-Pins


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  • Does ibrutinib cause cryptococcosis in patients with chronic lymphocytic leukemia?

    Disseminated cryptococcosis with brain involvement in patients with chronic lymphoid malignancies on ibrutinib. Open Forum Infect Dis. 2017;4:ofw261. Okamoto K, Proia LA, Demarais PL. Disseminated cryptococcal disease in a patient with chronic lymphocytic leukemia on ibrutinib. Case Rep Infect Dis. 2016;2016:4642831.

  • Does levofloxacin reduce mortality in children with acute leukaemia?

    For patients undergoing HCT, levofloxacin was given from day −2 until engraftment. In these studies, antibacterial prophylaxis did not significantly reduce mortality in children with acute leukaemia and those undergoing HCT (0–6% in the control groups).

  • Should antibiotic therapy be discontinued in neutropenic leukaemia patients?

    Lancet Oncol 2014; 15: e327–40. Discontinuation of empirical antibiotic therapy in neutropenic leukaemia patients with fever of unknown origin is ethical.

  • Do immunotherapeutic and molecular targeted antineoplastic agents prevent infections in leukemia patients?

    This position paper updates our knowledge of infections associated with these agents and provides recommendations for a rational clinical management of prevention and treatment of infections in leukemia patients treated with immunotherapeutic and molecular targeted antineoplastic agents, given with or without standard therapy.

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