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ANTIDOTE CHART

ANTIDOTE CHART ***This poster is not intended for individual patient care If you are caring for a known or suspected poisoned patient contact your regional poison center for patient-specific recommendations*** Oklahoma Center for Poison & Drug Information Health Professional Line: 877-271-6998 OklahomaPoison August 2017

Are there antidotes for overdose & intoxication?
While for many overdoses and intoxications the treatment involves supportive care and treatment of the sequelae there are specific antidotes available for a variety of substances. Identifying the ingestion and prompt administration of the correct antidote can prevent significant morbidity and mortality for many patients.
Are antidotes safe?
When antidotes are administered appropriately, they may limit morbidity and mortality as demonstrated in paracetamol and digitalis overdose. 2 On the other hand, if unavailable or used inappropriately, the patient may suffer adverse effects from the poison or the antidote, respectively. WHAT IS AN ANTIDOTE?
How do antidotes mediate the effect of a poison or toxin?
Indian J Crit Care Med. 2019 Dec; 23 (Suppl 4): S241–S249. Antidotes are agents that negate the effect of a poison or toxin. Antidotes mediate its effect either by preventing the absorption of the toxin, by binding and neutralizing the poison, antagonizing its end-organ effect, or by inhibition of conversion of the toxin to more toxic metabolites.
What is an antidote in a hospital?
An antidote is a substance that can counteract a form of poisoning. The term antidote is a Greek word meaning “given against”. This post will help you familiarize yourself with the common antidotes that are used in the hospital setting.

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