1,25-dihydroxycholecalciferol - NCBI


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PDF Identification of 125-Dihydroxycholecalciferol aNew Kidney

A vitamin D metabolite 25-dihydroxy cholecalciferol is further hydroxylated by kidney before acting as a hormone on target tissues The structure of this kidney metabolite is now described

PDF 125-dihydroxycholecalciferol: endocrinology meets the immune

125-Dihydroxycholecalciferol: Type 1 diabetes: NOD mice DC dendritic cells; 125(OH)The activated form of vitamin D 125-dihydroxychole-2 D 3 125-dihydroxycholecalciferol; NOD non-obese diabetic; Th T-helper calciferol (125(OH) 2D 3) is well known for its effects on Ca and bone metabolism but also non-classical effects of the

  • Does cholecalciferol have immunomodulatory effects?

    Previous work has demonstrated that, besides its effects on Ca and bone metabolism, the active form of cholecalciferol, 1,25-dihydroxycholecalciferol (1,25(OH)2D3), possesses pronounced immunomodulatory effects.

  • Does nephrectomy prevent bone calcium mobilization response to 25-hydroxycholecalciferol?

    1,25-dihydroxycholecalciferol: metabolite of vitamin D3 active on bone in anephric rats Nephrectomy prevents completely the bone calcium mobilization response to 25-hydroxycholecalciferol. In contrast it does not prevent this response to 1,25-dihydroxycholecalciferol.

  • How is 125-dihydroxycholecalciferol identified?

    The molecule has been identified as 1,25-dihydroxycholecalciferol by means of mass spectrometry, ultraviolet absorption spectrophotometry, and specific chemical reactions. Full text is available as a scanned copy of the original print version.

  • Which metabolite is more polar than 25-hydroxycholecalciferol?

    Proc Natl Acad Sci U S A. 1971 Apr; 68 (4): 803–804. A biologically active vitamin D 3 metabolite (“peak V metabolite”) more polar than 25-hydroxycholecalciferol has been isolated from chicken intestines in pure form as a mono (trimethylsilyl)ether derivative.

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