antibodies function to fight infection


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PDF Introduction to Antibody Structure/Function

Med Chem 528 Origins of antibodies Product of the adaptive immune system B cells (antibody based immunity) T cells (cell based immunity) Pre-exposure protects against subsequent infection Bacteria viruses toxins Plasma from exposed mice can confer protection to naïve mice Infants protected by maternal antibodies Mediate most allergic responses

  • How do antibodies combat viral infections?

    Antibodies can combat viral infections through several mechanisms. First, antibodies can prevent viral glycoproteins of enveloped viruses or the protein shell of non-enveloped viruses from binding to the target host cells 8, 9.

  • What role do antibodies play in a host defense against pathogens?

    Antibodies play an essential role in host defence against pathogens by binding to microorganisms and infected cells and exerting various effector functions. In this Review, Lu and colleagues summarize antibody isotypes and subclasses, modifications, receptor binding and signalling and effector functions in the context of infectious diseases.

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